| 目次 |
| 述评 |
| X射线FLASH放射治疗的射线来源、计量与防护研究现状 ------------------------------------------------------------------------------------------------------------------------1041 吴岱 羊奕伟 张毅 唐瑛鸿 胡旭林 王青青 |
| FLASH放疗：从基础研究到临床转化的革命性探索 ------------------------------------------------------------------------------------------------------------------------1047 曹志飞 杜小波 |
| 专家共识 |
| 高能X射线FLASH照射临床前研究专家共识 ------------------------------------------------------------------------------------------------------------------------1052 中国医学装备协会放射治疗设备与技术分会 |
| FLASH放疗剂量学与临床前研究 |
| FLASH放疗中不同氧含量下束流时间结构驱动的自由基动力学研究 ------------------------------------------------------------------------------------------------------------------------1061 孙健涵 孔祥慧 吕建锋 王景辉 刘小冬 林晨 黎田 张艺宝 黄森林 |
| X射线FLASH照射与常规剂量率照射对小鼠脑组织辐射损伤的影响 ------------------------------------------------------------------------------------------------------------------------1069 王远旭 李金华 唐宇凤 |
| 超高剂量率与常规剂量率全腹照射对小鼠急性放射性肠损伤的剂量效应差异 ------------------------------------------------------------------------------------------------------------------------1077 申玉凤 周杰 李林涛 耿凤豪 杨晨曦 陈小花 王硕 唐炜 李永杰 路顺 |
| FLASH照射对小鼠肠道急性放射损伤的机制研究 ------------------------------------------------------------------------------------------------------------------------1085 刘小曼 刘雅妮 李志慧 闫栋斐 张利辉 李梦华 李少斌 董国福 王长振 |
| 重离子FLASH照射减轻急性肠道损伤及其调控机制 ------------------------------------------------------------------------------------------------------------------------1092 杨雨晨 韩佳颖 李小波 张俊昱 周利荣 石健 邓小武 朱红玉 |
| 质子FLASH照射和常规照射对肾癌细胞周期和死亡的影响 ------------------------------------------------------------------------------------------------------------------------1100 张俊 张思倩 王巧娟 隋丽 张永胜 曹志飞 |
| 质子FLASH照射对人肝细胞及肝癌细胞辐射损伤比较 ------------------------------------------------------------------------------------------------------------------------1107 汪越 隋丽 王巧娟 刘建成 苏鹏 黄志豪 |
| FLASH照射的氧消耗与氧效应研究 ------------------------------------------------------------------------------------------------------------------------1115 罗辉 杨成梁 Paola Ballesteros-Zebadua Javier Franco-Perez 袁期刚 马蕾杰 毛荣虎 雷宏昌 孙亚楠 宋帅 葛红 |
| 超高剂量率照射下乳腺癌细胞的短期能量代谢变化 ------------------------------------------------------------------------------------------------------------------------1122 罗筠彬 张嘉瑛 吕建锋 王鹤茗 薛丽香 王皓 杨根 颜学庆 |
| FLASH照射与常规照射在乳腺癌的肿瘤控制和代谢途径改变的比较 ------------------------------------------------------------------------------------------------------------------------1130 商航 陆星宇 崔靓 周凌宏 |
| 质子超高剂量率照射对人肺上皮细胞与肺癌细胞系内质网应激通路的差异化调控 ------------------------------------------------------------------------------------------------------------------------1138 王笑菲 周光明 胡文涛 |
| 基于EBT4胶片的FLASH放疗快速精确剂量测量研究与应用 ------------------------------------------------------------------------------------------------------------------------1144 张毅 羊奕伟 唐瑛鸿 王诗岚 吴鹏 杨沁 黄旭帆 罗银 蒋雨 罗文俊 邹贵强 冯化 胡银祥 |
| 基于Geant4的9 MeV电子线FLASH治疗室的辐射场分布研究 ------------------------------------------------------------------------------------------------------------------------1152 程德琪 杨沁 黄旭帆 吴鹏 谢浩然 夏静 汪二峰 于国福 蒋雨 刘贤洪 |
| FLASH照射的微观尺度蒙特卡罗模拟研究进展 ------------------------------------------------------------------------------------------------------------------------1157 朱红玉 胡安康 赖有方 杨雨晨 邓小武 |
| 消息 |
| 《Radiation Medicine and Protection》入选“中国科技核心期刊” ------------------------------------------------------------------------------------------------------------------------1068 |
| 读者·作者·编者 |
| 本刊可直接使用缩写形式的常用词汇 ------------------------------------------------------------------------------------------------------------------------1060 |
| 常见基金项目的英文名称 ------------------------------------------------------------------------------------------------------------------------1076 |
| 论文参考文献中电子期刊及著作或编著的著录格式 ------------------------------------------------------------------------------------------------------------------------1091 |
| 关于量和单位的规范 ------------------------------------------------------------------------------------------------------------------------1099 |
| 作者投稿时语言文字上应注意的几个问题 ------------------------------------------------------------------------------------------------------------------------1106 |
| 本刊对论文中化学元素与核素符号书写的要求 ------------------------------------------------------------------------------------------------------------------------1151 |
| 《中华放射医学与防护杂志》稿约见本卷第1期第80~82页，第7期第718~720页 《中华放射医学与防护杂志》第十一届编辑委员会组成人员名单见英文目次后 |
| 本期执行主编 孙全富 卓维海 |
| 本期特邀专家 吴岱 张舒羽 周美娟 邓小武 路顺 杜乐辉 杨根 黄森林 曹志飞 胡文涛 周凌宏 朱红玉 罗辉 羊奕伟 刘德明 |
| 责任编辑 张琳 英文编辑 郝建中 |
| CONTENTS IN BRIEF |
| Editorials |
| Current status of radiation sources, meterage and protection in X-ray FLASH radiotherapy ------------------------------------------------------------------------------------------------------------------------1041 Wu Dai, Yang Yiwei, Zhang Yi, Tang Yinghong, Hu Xulin, Wang Qingqing |
| FLASH radiotherapy: pioneering the revolutionary path from bench to bedside ------------------------------------------------------------------------------------------------------------------------1047 Cao Zhifei, Du Xiaobo |
| Guidelines and consensus |
| Expert consensus on preclinical research into high-energy X-ray FLASH irradiation ------------------------------------------------------------------------------------------------------------------------1052 Radiotherapy Equipment and Technology Branch of China Medical Equipment Association |
| FLASH radiotherapy dosimetry and preclinical studies |
| Study on the radical kinetics driven by the beam time profile under different oxygen contents in FLASH radiotherapy ------------------------------------------------------------------------------------------------------------------------1061 Sun Jianhan, Kong Xianghui, Lyu Jianfeng, Wang Jinghui, Liu Xiaodong, Lin Chen, Li Tian, Zhang Yibao, Huang Senlin |
| Effects of X-ray FLASH irradiation and conventional-dose-rate irradiation on radiation-induced injury to the brain tissue of mice ------------------------------------------------------------------------------------------------------------------------1069 Wang Yuanxu, Li Jinhua, Tang Yufeng |
| Differences in dose-response effects between ultra-high dose rate and conventional dose rate whole abdominal irradiation on acute radiation-induced intestinal injury in mice ------------------------------------------------------------------------------------------------------------------------1077 Shen Yufeng, Zhou Jie, Li Lintao, Geng Fenghao, Yang Chenxi, Chen Xiaohua, Wang Shuo, Tang Wei, Li Yongjie, Lu Shun |
| Mechanisms of FLASH irradiation on acute radiation-induced intestinal injury in mice ------------------------------------------------------------------------------------------------------------------------1085 Liu Xiaoman, Liu Yani, Li Zhihui, Yan Dongfei, Zhang Lihui, Li Menghua, Li Shaobin, Dong Guofu, Wang Changzhen |
| Heavy-ion FLASH irradiation mitigates acute intestinal injury and its regulatory mechanisms ------------------------------------------------------------------------------------------------------------------------1092 Yang Yuchen, Han jiaying, Li Xiaobo, Zhang Junyu, Zhou Lirong, Shi Jian, Deng Xiaowu, Zhu Hongyu |
| Effects of proton FLASH irradiation and conventional irradiation on the cell cycle and death of renal cancer cells ------------------------------------------------------------------------------------------------------------------------1100 Zhang Jun, Zhang Siqian, Wang Qiaojuan, Sui Li, Zhang Yongsheng, Cao Zhifei |
| Comparative study on the radiation damage of proton FLASH irradiation to human hepatocytes and hepatocellular carcinoma cells ------------------------------------------------------------------------------------------------------------------------1107 Wang Yue, Sui Li, Wang Qiaojuan, Liu Jiancheng, Su Peng, Huang Zhihao |
| Study on oxygen depletion and oxygen effect of FLASH irradiation ------------------------------------------------------------------------------------------------------------------------1115 Luo Hui, Yang Chengliang, Paola Ballesteros-Zebadua, Javier Franco-Perez, Yuan Qigang, Ma Leijie, Mao Ronghu, Lei Hongchang, Sun Yanan, Song Shuai, Ge Hong |
| Short-term changes in energy metabolism of breast cancer cells under ultra-high dose rate irradiation ------------------------------------------------------------------------------------------------------------------------1122 Luo Yunbin, Zhang Jiaying, Lyu Jianfeng, Wang Heming, Xue Lixiang, Wang Hao, Yang Gen, Yan Xueqing |
| Comparison of tumor control and metabolic pathway changes between FLASH irradiation and conventional irradiation in breast cancer ------------------------------------------------------------------------------------------------------------------------1130 Shang Hang, Lu Xingyu, Cui Liang, Zhou Linghong |
| Differential endoplasmic reticulum stress signaling underlies the FLASH effect in human lung epithelial and lung cancer cells ------------------------------------------------------------------------------------------------------------------------1138 Wang Xiaofei, Zhou Guangming, Hu Wentao |
| A study and application of rapid and precise dose measurement based on Gafchromic EBT4 film in FLASH radiotherapy ------------------------------------------------------------------------------------------------------------------------1144 Zhang Yi, Yang Yiwei, Tang Yinghong, Wang Shilan, Wu Peng, Yang qin, Huang Xufan, Jiang Yu, Luo Wenjun, Zou Guiqiang, Feng Hua, Hu Yinxiang |
| A Geant4-based research on radiation field distribution in a 9 MeV e-FLASH treatment room ------------------------------------------------------------------------------------------------------------------------1152 Cheng Deqi, Yang Qin, Huang Xufan, Wu Peng, Xie Haoran, Xia Jing, Wang Erfeng, Yu Guofu, Jiang Yu, Liu Xianhong |
| Research advances in microscopic Monte Carlo simulations of FLASH irradiation ------------------------------------------------------------------------------------------------------------------------1157 Zhu Hongyu, Hu Ankang, Lai Youfang, Yang Yuchen, Deng Xiaowu |