| Wu Dai,Yang Yiwei,Zhang Yi,et al.Current status of radiation sources, meterage and protection in X-ray FLASH radiotherapy[J].Chinese Journal of Radiological Medicine and Protection,2025,45(11):1041-1046 |
| Current status of radiation sources, meterage and protection in X-ray FLASH radiotherapy |
| Received:October 24, 2025 |
| DOI：10.3760/cma.j.cn112271-20251024-00370 |
| KeyWords:FLASH radiotherapy X-rays Radiation sources Dosimetry |
| FundProject:国家自然科学基金(12375318) |
| Author Name | Affiliation | | Wu Dai | Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900, China | | Yang Yiwei | Institute of Applied Electronics, China Academy of Engineering Physics, Mianyang 621900, China | | Zhang Yi | Department of Oncology, Affiliated Hospital of Guizhou Medical University & Affiliated Cancer Hospital of Guizhou Medical University, Guiyang 550024, China
School of Nuclear Science and Technology, Lanzhou University, Lanzhou 730000, China | | Tang Yinghong | College of Nuclear Technology and Automation Engineering, Chengdu University of Technology, Chengdu 610000, China | | Hu Xulin | School of Information and Control Engineering, Southwest University of Science and Technology, Mianyang 621010, China | | Wang Qingqing | School of Information and Control Engineering, Southwest University of Science and Technology, Mianyang 621010, China |
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| Abstract:: |
| International studies have established that electrons, X-rays, protons, and heavy ions can all be utilized in ultra-high dose-rate radiotherapy. Among these modalities, megavoltage X-ray ultra-high dose-rate radiotherapy holds particularly broad clinical promise. With its long-term expertise in high-intensity pulsed radiation sources, the Institute of Applied Electronics at the China Academy of Engineering Physics has pioneered global solutions for generating and measuring megavoltage X-rays ultra-high dose-rate radiotherapy, positioning China at the forefront of this field. Herein, we review the development history, current status, and future trends in ultra-high dose-rate X-ray generation, measurement, and protection. The insights provided aim to serve as a reliable reference for clinical and preclinical research, equipment development, and standardization, thereby enabling more precise and reliable megavoltage ultra-high dose-rate X-ray production and measurement. We hope this work will significantly support further research and clinical translation of ultra-high dose-rate radiotherapy technology. |
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