Li Fei,Zhao Hongfu.Advances in the application of spatially fractionated radiation therapy as a palliative radiotherapy technique[J].Chinese Journal of Radiological Medicine and Protection,2025,45(7):712-720
Advances in the application of spatially fractionated radiation therapy as a palliative radiotherapy technique
Received:January 20, 2025  
DOI：10.3760/cma.j.cn112271-20250120-00025
KeyWords:Spatially fractionated radiation therapy (SFRT)  Palliative radiotherapy  Dosimetry
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Author NameAffiliationE-mail
Li Fei Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun 130033, China  
Zhao Hongfu Department of Radiation Oncology, China-Japan Union Hospital of Jilin University, Changchun 130033, China zhaohf@jlu.edu.cn 
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Abstract::
      Spatially fractionated radiation therapy (SFRT) dates from 1909. With the development of radiotherapy technologies and radiobiological theories, advances have been made in both the connotation and implementation method of SFRT. Additionally, clinical outcomes have further corroborated the role of SFRT as a palliative radiotherapy technique. This review summarizes the advances in the application of SFRT as a palliative radiotherapy technique from the aspects of the development history and related technologies, radiobiological basis, and clinical applications, in order to offer a reference for the implementation of SFRT.
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