| Li Huayu,Song Jiaying,Ye Tao,et al.Advances in the application of PET/CT molecular imaging probes to the treatment of breast cancer[J].Chinese Journal of Radiological Medicine and Protection,2025,45(5):497-502 |
| Advances in the application of PET/CT molecular imaging probes to the treatment of breast cancer |
| Received:December 12, 2024 |
| DOI：10.3760/cma.j.cn112271-20241212-00474 |
| KeyWords:Breast cancer Radiopharmaceutical Positron emission tomography/computed tomography (PET/CT) Molecular imaging |
| FundProject:浙江省自然科学基金(Y24H160037);宁波市自然科学基金(2023J021);宁波市科技计划项目(鄞科2016-87) |
| Author Name | Affiliation | E-mail | | Li Huayu | Department of Radiology, the Affiliated People's Hospital of Ningbo University, Ningbo 315040, China | | | Song Jiaying | Department of Radiology, the Affiliated People's Hospital of Ningbo University, Ningbo 315040, China | | | Ye Tao | Department of Radiology, the Affiliated People's Hospital of Ningbo University, Ningbo 315040, China | | | Wang Yucong | Department of Radiology, the Affiliated People's Hospital of Ningbo University, Ningbo 315040, China | | | Wang Lianfu | Department of Radiology, the Affiliated People's Hospital of Ningbo University, Ningbo 315040, China | | | Li Qiang | Department of Radiology, the Affiliated People's Hospital of Ningbo University, Ningbo 315040, China | rmliqiang@nbu.edu.cn |
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| Abstract:: |
| Breast cancer, a malignant tumor that significantly endangers women's health, has shown a gradually rising incidence in recent years. Some breast cancer patients experienced poor prognosis. The commonly used imaging techniques for breast cancer include ultrasound, mammography, and magnetic resonance (MR), which suffer from certain limitations in accurately diagnosing and staging breast cancer. Positron emission tomography/computed tomography (PET/CT) enables tumor imaging at the cellular and molecular levels by utilizing radiolabeled molecular probes targeting different ligands. This technique facilitates precise localization and qualitative diagnosis of lesions to improve the staging accuracy, thereby reducing biopsy frequency and enhancing treatment effects for patients. Therefore, PET/CT has gradually developed into an essential imaging method for breast cancer in clinical practice. It plays a critical role in assessing the extent of lesion invasion, predicting immune subtypes, and estimating targeted therapy efficacy, holding promising application prospects. Recently, significant research breakthroughs have been achieved in this field. This review summarized the advances in clinical applications of different PET/CT molecular probes in the diagnosis and treatment of breast cancer, aiming to enhance the understanding of this aspect. |
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