Tang Yujie,Liu Chuanfeng,Wang Guanbo,et al.Preliminary study of the dose characterization of the INTRABEAM system[J].Chinese Journal of Radiological Medicine and Protection,2025,45(5):472-477
Preliminary study of the dose characterization of the INTRABEAM system
Received:November 13, 2024  
DOI:10.3760/cma.j.cn112271-20241113-00437
KeyWords:Electronic brachytherapy  Monte Carlo  Dose characterization  Percent depth dose
FundProject:国家重点研发计划(2023YFF0613503);中国计量科学研究院基本科研业务费(AKYZZ2423)
Author NameAffiliationE-mail
Tang Yujie East China University of Technology, Nanchang 330013, China
National Institute of Metrology of China, Beijing 100029, China 
 
Liu Chuanfeng National Institute of Metrology of China, Beijing 100029, China  
Wang Guanbo East China University of Technology, Nanchang 330013, China
National Institute of Metrology of China, Beijing 100029, China 
 
Li Dehong National Institute of Metrology of China, Beijing 100029, China lidh@nim.ac.cn 
Liu Yibao East China University of Technology, Nanchang 330013, China  
Dai Tiantian Department of Radiation Oncology, China-Japan Friendship Hospital, Beijing 100029, China  
Wang Huagui East China University of Technology, Nanchang 330013, China
National Institute of Metrology of China, Beijing 100029, China 
 
Zhang Xiaole National Institute of Metrology of China, Beijing 100029, China  
Cheng Jianbo National Institute of Metrology of China, Beijing 100029, China  
Huang Jianwei National Institute of Metrology of China, Beijing 100029, China  
Zhang Xuan National Institute of Metrology of China, Beijing 100029, China  
Shi Taiwei National Institute of Metrology of China, Beijing 100029, China  
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Abstract::
      Objective To investigate the dose characteristics of the Zeiss INTRABEAM system in air and water, providing dose reference for electronic brachytherapy. Methods A Monte Carlo program was used to establish a three-dimensional model of a miniature X-ray source vacuum drift tube and a 4 cm spherical applicator. The process of electron beam bombardment on a gold target to generate X-rays was simulated, and parameters such as photon fluence spectrum, percentage depth dose, and half-value layer were calculated. Additionally, the radial dose uniformity in water was measured. Results The average energy of X-rays at 3 cm in air was 20.8 keV, with a half-value layer of 0.08 mm Al. Under the influence of the applicator, the spectrum becomes hardened, with axial and radial average energies of 28.7 and 29.0 keV, respectively. In water, the percentage depth dose (PDD) curve follows an inverse cubic decay with depth, indicating strong dose concentration and rapid fall-off in near-field irradiation. The radial dose uniformity in water exceeded 99.5%. Conclusions The INTRABEAM device emits low-energy X-rays characterized by shallow penetration depth, and concentrated dose delivery. Its highly uniform dose distribution ensures comprehensive coverage of the target area, making it particularly suitable for treating superficial tumors and for intraoperative radiotherapy at close range.
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