| Tang Yujie,Liu Chuanfeng,Wang Guanbo,et al.Preliminary study of the dose characterization of the INTRABEAM system[J].Chinese Journal of Radiological Medicine and Protection,2025,45(5):472-477 |
| Preliminary study of the dose characterization of the INTRABEAM system |
| Received:November 13, 2024 |
| DOI：10.3760/cma.j.cn112271-20241113-00437 |
| KeyWords:Electronic brachytherapy Monte Carlo Dose characterization Percent depth dose |
| FundProject:国家重点研发计划(2023YFF0613503);中国计量科学研究院基本科研业务费(AKYZZ2423) |
| Author Name | Affiliation | E-mail | | Tang Yujie | East China University of Technology, Nanchang 330013, China
National Institute of Metrology of China, Beijing 100029, China | | | Liu Chuanfeng | National Institute of Metrology of China, Beijing 100029, China | | | Wang Guanbo | East China University of Technology, Nanchang 330013, China
National Institute of Metrology of China, Beijing 100029, China | | | Li Dehong | National Institute of Metrology of China, Beijing 100029, China | lidh@nim.ac.cn | | Liu Yibao | East China University of Technology, Nanchang 330013, China | | | Dai Tiantian | Department of Radiation Oncology, China-Japan Friendship Hospital, Beijing 100029, China | | | Wang Huagui | East China University of Technology, Nanchang 330013, China
National Institute of Metrology of China, Beijing 100029, China | | | Zhang Xiaole | National Institute of Metrology of China, Beijing 100029, China | | | Cheng Jianbo | National Institute of Metrology of China, Beijing 100029, China | | | Huang Jianwei | National Institute of Metrology of China, Beijing 100029, China | | | Zhang Xuan | National Institute of Metrology of China, Beijing 100029, China | | | Shi Taiwei | National Institute of Metrology of China, Beijing 100029, China | |
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| Abstract:: |
| Objective To investigate the dose characteristics of the Zeiss INTRABEAM system in air and water, providing dose reference for electronic brachytherapy. Methods A Monte Carlo program was used to establish a three-dimensional model of a miniature X-ray source vacuum drift tube and a 4 cm spherical applicator. The process of electron beam bombardment on a gold target to generate X-rays was simulated, and parameters such as photon fluence spectrum, percentage depth dose, and half-value layer were calculated. Additionally, the radial dose uniformity in water was measured. Results The average energy of X-rays at 3 cm in air was 20.8 keV, with a half-value layer of 0.08 mm Al. Under the influence of the applicator, the spectrum becomes hardened, with axial and radial average energies of 28.7 and 29.0 keV, respectively. In water, the percentage depth dose (PDD) curve follows an inverse cubic decay with depth, indicating strong dose concentration and rapid fall-off in near-field irradiation. The radial dose uniformity in water exceeded 99.5%. Conclusions The INTRABEAM device emits low-energy X-rays characterized by shallow penetration depth, and concentrated dose delivery. Its highly uniform dose distribution ensures comprehensive coverage of the target area, making it particularly suitable for treating superficial tumors and for intraoperative radiotherapy at close range. |
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