| Yang Siyu,Niu Xiaofeng,Deng Lijuan,et al.Advances in applications of single-cell RNA sequencing to research on radiation-induced injuries[J].Chinese Journal of Radiological Medicine and Protection,2025,45(3):249-254 |
| Advances in applications of single-cell RNA sequencing to research on radiation-induced injuries |
| Received:May 07, 2024 |
| DOI：10.3760/cma.j.cn112271-20240507-00168 |
| KeyWords:Single-cell RNA sequencing (scRNA-Seq) Radiation-induced injury Ionizing radiation |
| FundProject:国家自然科学基金(82060313);云南省基础研究专项(202201AW070002);云南省科技人才与平台计划(202305AC160020) |
| Author Name | Affiliation | E-mail | | Yang Siyu | Department of Radiology, Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University), Kunming 650118, China | | | Niu Xiaofeng | Department of Radiology, Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University), Kunming 650118, China | | | Deng Lijuan | Department of Radiology, Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University), Kunming 650118, China | | | Ren Zheng | Department of Radiology, Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University), Kunming 650118, China | | | Yang Jun | Department of Radiology, Yunnan Cancer Hospital (The Third Affiliated Hospital of Kunming Medical University), Kunming 650118, China | imdyang@qq.com |
|
| Hits: 2564 |
| Download times: 1032 |
| Abstract:: |
| Radiotherapy can cause varying degrees of damage to surrounding normal tissues while treating tumors. In recent years, single-cell RNA sequencing (scRNA-Seq), an emerging technology in modern biology, has gradually played a significant role in research on radiation-induced injuries. Researchers have delved into a variety of radiation-induced brain injuries, including radiation-induced brain injury (RIBI), cardiovascular injury, lung injury, intestinal injury, skin injury, and hematopoietic injury. Their studies provide novel perspectives for revealing the mechanisms behind radiation-induced injuries, assessing the degree of injury, and exploring potential therapies. This study reviews the advances in the application of scRNA-seq to research on radiation-induced injuries. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
