| Wang Liang,Lin Hailei,Ji Yanqin.Advances in research on the application of magnetic ferrite nanoparticles in radiotherapy[J].Chinese Journal of Radiological Medicine and Protection,2025,45(1):74-79 |
| Advances in research on the application of magnetic ferrite nanoparticles in radiotherapy |
| Received:July 12, 2024 |
| DOI：10.3760/cma.j.cn112271-20240712-00260 |
| KeyWords:Magnetic ferrite nanoparticles Malignant tumors Radiotherapy Radiosensitivity |
| FundProject: |
| Author Name | Affiliation | E-mail | | Wang Liang | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Lin Hailei | Department of Radiation Oncology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing 100730, China | | | Ji Yanqin | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | jiyanqin@nirp.chinacdc.cn |
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| Abstract:: |
| Radiation-induced adverse reactions in organs at risk (OAR) is recognized as a significant factor limiting doses to clinical target volumes (CTV). Magnetic ferrite nanoparticles, distinguished by their unique physicochemical properties such as ease of modification and high biocompatibility, have been extensively investigated in the biomedical field. This article reviews the latest advances in research on the application of magnetic ferrite nanoparticles in radiotherapy, focusing on their magnetothermal effect, dose enhancement effect, promotion of ferroptosis, regulation of the cell cycle, and improvement in image-guided quality. Furthermore, this article provides an outlook for future research. |
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