| Li Yun,Liu Xixia.Research progress on the pathogenesis and rehabilitation strategies of radiation-induced muscle fibrosis[J].Chinese Journal of Radiological Medicine and Protection,2024,44(11):985-990 |
| Research progress on the pathogenesis and rehabilitation strategies of radiation-induced muscle fibrosis |
| Received:February 05, 2024 |
| DOI：10.3760/cma.j.cn112271-20240205-00047 |
| KeyWords:Radiation-induced muscle fibrosis Transforming growth factor-β Connective tissue growth factor Cancer-associated fibroblast Rehabilitation strategy |
| FundProject:广西自然科学基金项目(2023GXNSFAA026175) |
| Author Name | Affiliation | E-mail | | Li Yun | Guangxi University of Chinese Medicine, Nanning 530219, China
Joint Training Base of Guangxi University of Chinese Medical, Department of Rehabilitation, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China | | | Liu Xixia | Joint Training Base of Guangxi University of Chinese Medical, Department of Rehabilitation, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning 530021, China
Guangxi Academy of Medical Sciences, Nanning 530021, China | liuxixia2008@126.com |
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| Abstract:: |
| Radiation-induced fibrosis, especially radiation-induced muscle fibrosis (RIMF), is a common complication associated with radiotherapy. After radiotherapy, there is a gradual worsening of muscle stiffness and joint mobility impairments over time, which severely affects the quality of life of cancer patients. This article aims to review the latest research progress on the mechanisms and diagnosis and assessment methods of RIMF, as well as its rehabilitation strategies. This review provides systematic and effective health management and rehabilitation strategies to improve the prognosis of patients with RIMF. |
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