Wang Youjia,Han Guang.Advances in research on treatment-associated pneumonitis in lung cancer patients treated with radiation combined with immunotherapy[J].Chinese Journal of Radiological Medicine and Protection,2024,44(8):711-717
Advances in research on treatment-associated pneumonitis in lung cancer patients treated with radiation combined with immunotherapy
Received:January 27, 2024  
DOI:10.3760/cma.j.cn112271-20240127-00034
KeyWords:Lung cancer  Radiotherapy  Immune checkpoint inhibitor  Radiation-induced immune-related pneumonitis
FundProject:中华国际医学交流基金中青年医学研究专项基金(Z-2014-06-2102);武汉市2022年度知识创新专项(2022020801010512);
Author NameAffiliationE-mail
Wang Youjia Department of Radiotherapy Center, Hubei Cancer Hospital, Tongji Medical College of Huazhong University of Science & Technology, Wuhan 430000, China  
Han Guang Department of Radiotherapy Center, Hubei Cancer Hospital, Tongji Medical College of Huazhong University of Science & Technology, Wuhan 430000, China hg7913@163.com 
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Abstract::
      Radiotherapy and immunotherapy prove significant for cancer treatment presently. Despite therapeutic effects, they carry risks of adverse reactions. The survival rates and quality of life of patients with thoracic malignancies frequently fail to fulfill expectations after they receive radiotherapy combined with immunotherapy. A major reason for this is the occurrence of treatment-associated pneumonitis. To gain a deeper understanding of the pneumonitis induced by radiotherapy combined with immunotherapy for lung cancer, this paper reviews the pathogenesis, incidence, risk factors, differential diagnosis, and treatment of such pneumonitis.
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