| Li Shuang,Liu Qingjie.Advances in research on the application of the expression analysis of radiation-responsive genes to biological dose estimation[J].Chinese Journal of Radiological Medicine and Protection,2024,44(8):704-710 |
| Advances in research on the application of the expression analysis of radiation-responsive genes to biological dose estimation |
| Received:March 13, 2024 |
| DOI：10.3760/cma.j.cn112271-20240313-00090 |
| KeyWords:Ionizing radiation Gene expression Biodosimetry Dose estimation |
| FundProject:国家自然科学基金(82173464,81803162,82173463) |
| Author Name | Affiliation | E-mail | | Li Shuang | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Liu Qingjie | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | liuqingjie@nirp.chinacdc.cn |
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| Abstract:: |
| Following large-scale nuclear and radiological emergencies, the accurate estimation of radiation doses can provide a crucial scientific basis for subsequent medical treatment and prognosis of acute radiation injury. In recent years, the expression analysis of radiation-responsive genes has emerged as an effective approach to dose classification and clinical risk prediction for a large population owing to its high speed and high throughput. This paper reviews the advances in research on the application of the expression analysis to biological dose estimation, with a view to promoting the popularization of this technology and to further enhancing China's capacity for radiation dose estimation. |
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