Wu Ting,Wu Linyu,Gao Chen,et al.Application and challenges of chest CT peritumoral radiomics in the precision diagnosis and treatment of non-small cell lung cancer[J].Chinese Journal of Radiological Medicine and Protection,2024,44(5):443-449 |
Application and challenges of chest CT peritumoral radiomics in the precision diagnosis and treatment of non-small cell lung cancer |
Received:August 26, 2023 |
DOI:10.3760/cma.j.cn112271-20230826-00063 |
KeyWords:Non-small cell lung cancer Peritumoral region Radiomics Computed tomography Precision diagnosis and treatment |
FundProject:国家自然科学基金(82102128);浙江省自然科学基金资助项目(LTGY23H180001);浙江省"尖兵""领雁"研发攻关计划(2022C03046);浙江省卫生健康科技计划项目(2022KY230);浙江中医药大学科研项目(2022FSYYZY08;2022JKJNTZ19;2021JKGJYY007) |
Author Name | Affiliation | E-mail | Wu Ting | Department of Radiology, First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China First Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, China | | Wu Linyu | Department of Radiology, First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China First Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, China | | Gao Chen | Department of Radiology, First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China First Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, China | | Lou Xinjing | Department of Radiology, First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China First Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, China | | Chen Jiawei | Department of Radiology, First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China First Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, China | | Wu Jun | Department of Radiology, First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China First Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, China | | Xu Maosheng | Department of Radiology, First Affiliated Hospital of Zhejiang Chinese Medical University(Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou 310006, China First Clinical Medicine College, Zhejiang Chinese Medical University, Hangzhou 310053, China | xums166@zcmu.edu.cn |
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Abstract:: |
By extracting quantitative radiomic features from regions of interest in medical images and correlating them with the biological features and heterogeneity of tumors, radiomics can provide critical information and a basis for personalized precision diagnosis and treatment. Peritumoral regions contain a wealth of microbiological information. Therefore, chest CT peritumoral radiomics, which can provide quantitative non-invasive assessment for patients with non-small cell lung cancer (NSCLC) by mining the deep heterogeneity of peritumoral regions, has broad prospects for future clinical applications. Given the rapid progress in computer and medical big data techniques, as well as the in-depth efforts in multi-center, high-quality, and large-sample data in the future, it is reasonably believed that radiomics research will be gradually normalized and reproducible. This is conducive to the translation and application of radiomics research to clinical practice, thus laying a foundation for personalized and accurate diagnosis, treatment, and follow-up for lung cancer patients. |
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