| Wang Zhi,Pan Yingzi,Chen Mingsheng,Wang Fengchao.Radiotherapy for head and neck cancer: oral complications and treatment[J].Chinese Journal of Radiological Medicine and Protection,2023,43(9):752-758 |
| Radiotherapy for head and neck cancer: oral complications and treatment |
| Received:May 16, 2023 |
| DOI：10.3760/cma.j.cn112271-20230516-00146 |
| KeyWords:Head and neck cancer Radiotherapy Oral mucosa Salivary glands Dental caries |
| FundProject:重庆市科技创新专项（cstc2018jcyj-yszxX0004）；重庆市自然科学基金（cstc2021jcyj-msxmX0237）；重庆市教育委员会科学技术研究项目（KJQN2021OO444） |
| Author Name | Affiliation | E-mail | | Wang Zhi | State Key Laboratory of Trauma and Chemical Poisoning, Stomatological Hospital of Chongqing Medical University, Institute of Nuclear Protection Medicine, Department of Military Preventive Medicine, Basic Medical School of the Army Medical University, Chongqing 400038, China | | | Pan Yingzi | State Key Laboratory of Trauma and Chemical Poisoning, Stomatological Hospital of Chongqing Medical University, Institute of Nuclear Protection Medicine, Department of Military Preventive Medicine, Basic Medical School of the Army Medical University, Chongqing 400038, China | | | Chen Mingsheng | State Key Laboratory of Trauma and Chemical Poisoning, Stomatological Hospital of Chongqing Medical University, Institute of Nuclear Protection Medicine, Department of Military Preventive Medicine, Basic Medical School of the Army Medical University, Chongqing 400038, China | | | Wang Fengchao | State Key Laboratory of Trauma and Chemical Poisoning, Stomatological Hospital of Chongqing Medical University, Institute of Nuclear Protection Medicine, Department of Military Preventive Medicine, Basic Medical School of the Army Medical University, Chongqing 400038, China | fengchao.w@foxmail.com |
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| Abstract:: |
| Radiotherapy, as a common modality for the treatment of head and neck cancer (HNC), frequently induces oral and maxillofacial complications. However, the complex tissues and diverse pathogeneses of these regions lead to limited treatment protocols and research progress currently. This paper systematically summarizes radiation-induced oral mucositis, salivary gland injury, and dental caries in radiotherapy for HNC and reviews existing pathogenetic hypotheses, treatment, and research progress. The purpose is to provide some reference for further research on relevant pathological mechanisms and the development of new preventive and treatment methods. |
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