| Deng Lin,Wang Shaoqing,Leng Xingli,Yao Peng,Li Cuicui.Research progress of radiation nephropathy[J].Chinese Journal of Radiological Medicine and Protection,2023,43(4):314-320 |
| Research progress of radiation nephropathy |
| Received:December 07, 2022 |
| DOI：10.3760/cma.j.cn112271-20221207-00474 |
| KeyWords:Radiation nephropathy Pathogenesis Cancer treatment |
| FundProject:中核医疗2021年度核医科技创新重点项目(ZHYLZD2021005);四川省中医药管理局中医药科研课题项目(2021MS517);北京医卫健康公益基金会医学科研项目(YWJKJJHKYJJ-KH19007) |
| Author Name | Affiliation | E-mail | | Deng Lin | Nephrology Department, Second Affiliated Hospital of Chengdu Medical College(Nuclear Industry No. 416 Hospital), Chengdu 610051, China | | | Wang Shaoqing | Nephrology Department, Second Affiliated Hospital of Chengdu Medical College(Nuclear Industry No. 416 Hospital), Chengdu 610051, China | wowosasa2003@163.com | | Leng Xingli | Nephrology Department, Second Affiliated Hospital of Chengdu Medical College(Nuclear Industry No. 416 Hospital), Chengdu 610051, China | | | Yao Peng | Nephrology Department, Second Affiliated Hospital of Chengdu Medical College(Nuclear Industry No. 416 Hospital), Chengdu 610051, China | | | Li Cuicui | Medical Examination Center, PLA Western Theater General Hospital, Chengdu 610083, China | |
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| Abstract:: |
| Radiotherapy is an important treatment for malignant tumors. However, it is also one cause of damage to local normal tissues, such as radiation nephropathy, which is frequently induced during the radiotherapy of abdominal and pelvic tumors. The exact pathogenesis of radiation nephropathy is still unclear and is believed to be related mainly to factors including oxidative stress, cell aging, and gene changes presently. Moreover, there is a lack of effective treatments for radiation nephropathy. With an increase in the survival of tumor patients, radiation nephropathy has received increasing attention. This article mainly reviewed the research progress of radiation nephropathy from the aspects of pathogenesis and treatments, aiming to provide a reference for the research and clinical diagnosis and treatment of radiation nephropathy. |
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