| Gao Jun,Zhu Yadi,Wang Yongfeng,et al.Development of dose verification methods for boron neutron capture therapy[J].Chinese Journal of Radiological Medicine and Protection,2023,43(3):228-233 |
| Development of dose verification methods for boron neutron capture therapy |
| Received:November 15, 2022 |
| DOI：10.3760/cma.j.cn112271-20221115-00448 |
| KeyWords:Boron neutron capture therapy Neutron dose measurement Dose verification |
| FundProject: |
| Author Name | Affiliation | E-mail | | Gao Jun | International Academy of Neutron Science, Qingdao 266199, China
Institute of Neutron Science(Chongqing) Co., Ltd., Chongqing 401331, China | | | Zhu Yadi | Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China
University of Science and Technology of China, Hefei 230026, China | | | Wang Yongfeng | International Academy of Neutron Science, Qingdao 266199, China
Institute of Neutron Science(Chongqing) Co., Ltd., Chongqing 401331, China | | | Jin Chufeng | International Academy of Neutron Science, Qingdao 266199, China | | | Ji Xiang | International Academy of Neutron Science, Qingdao 266199, China | xiang.ji@fds.org.cn |
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| Abstract:: |
| To summarize the progress in BNCT dose verification method in the world and discusses their development prospects. Boron neutron capture therapy (BNCT) utilizes the specific capture reaction between the neutrons and boron drugs enriched in tumor cells to selectively kill tumor cells. In order to verify the accuracy of the radiotherapy plan and ensure the therapeutic effect on patients, it is necessary to measure the dose before treatment and compare the experimental radiation dose with the planned dose. The current BNCT dose measurement method mainly include point dose measurement method based on ionization chambers, thermoluminescence dosimeters and activation foils, two-dimensional dose measurement method based on films, and three-dimensional dose measurement method based on gel dosimeters. |
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