Li Beibei,Zhang Zijing,Zhao Mingyue,Wang Xu,Fan Yong,Wang Shigeng,Tong Xiaoyu,Wei Wei,Liu Yijun.Feasibility of individualized low radiation dose chest enhanced CT imaging: phantom and clinical study[J].Chinese Journal of Radiological Medicine and Protection,2022,42(12):992-998 |
Feasibility of individualized low radiation dose chest enhanced CT imaging: phantom and clinical study |
Received:August 03, 2022 |
DOI:10.3760/cma.j.cn112271-20220803-00315 |
KeyWords:Individualized|ODM|Low radiation dose|Computed tomography |
FundProject: |
Author Name | Affiliation | E-mail | Li Beibei | The First Hospital of Dalian Medical University, Dalian 116011, China | | Zhang Zijing | Shenzhen Hospital of Peking University, Shenzhen 518000, China | | Zhao Mingyue | The First Hospital of Dalian Medical University, Dalian 116011, China | | Wang Xu | The First Hospital of Dalian Medical University, Dalian 116011, China | | Fan Yong | The First Hospital of Dalian Medical University, Dalian 116011, China | | Wang Shigeng | The First Hospital of Dalian Medical University, Dalian 116011, China | | Tong Xiaoyu | The First Hospital of Dalian Medical University, Dalian 116011, China | | Wei Wei | The First Hospital of Dalian Medical University, Dalian 116011, China | | Liu Yijun | The First Hospital of Dalian Medical University, Dalian 116011, China | yijunliu@126.com |
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Abstract:: |
Objective To investigate the effect of the combination of Auto-prescription and ODMfull on image quality and radiation dose of chest enhanced CT inorder to explore the feasibility of individualized low radiation dose chest enhanced CT.Methods The phantoms PH-75 in two sizes were scanned with four scanning modes: group A, 120 kVp + Smart-mA; group B, 120 kVp + Smart-mA+ODMfull; group C, Auto-prescription + Smart-mA; group D, Auto-prescription + Smart-mA+ ODMfull. The images of each group were reconstructed with 40%-80% ASIR-V (interval 20%), recorded as A1-3-D1-3. Image quality and radiation dose were evaluated in order to obtain optimal scanning modes. Totally 35 cases(from the First Hospital of Dalian Medical University during November 2021 to July 2022) of chest enhancement CT were collected prospectively in the clinical study using the parameters of D2 group recorded as Dpatients. Patients in this group received chest enhancement CT scanning for the second time within three months. The CT parameters in first enhanced scanning recorded as Apatient were as same as those in group A1, and the parameters in second scanning recorded as Dpatient were as same as those in group D2. The SNRs, CNRs, subjective grading and imaging findings of the lesion in two groups were compared.Results In phantom study, the radiation dose of each group was statistically significant, and that in D group was the lowest. For two sizes of phantoms, A1 was uesd as the control group in pairwise comparison. The SDs of B1, C1, and D2 images had no statistical difference with that of A1 (P > 0.05), and SD of D1was higher than that of A1, and SDs of other groups were lower than that of A1(F=10.77,122.50, P<0.05). CNR of B1 had no statistical difference with that of A1, and the CNRs of other groups were higher(F=136.20,30.21, P<0.05). Subjective scores of A2, C2, D2 had no statistical difference with that of A1 and those of other groups were lower than that of A1(H=52.89,43.95, P<0.05). In clinical study, 80 kVp was uesd for 22 cases and 100 kVp was used for 13 cases in Dpatients group. SNRs and CNRs in the Dpatients group were all higher than those in the Apatients group (P > 0.05). The consistency of image quality scores for two observers was good (kappa = 0.754, P < 0.05). The median scores of the two groups were (4, 4).Conclusion Auto-prescription combined with ODMfull in chest enhanced CT imaging can achieve individualized low radiation dose with meeting the requirements of image quality and clinical diagnosis. |
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