Zhou Zhen,Yang Bo,Wang Zhiqun,Zhu Heling,Meng Xiangyin,Dong Tingting,Qiu Jie.The application of the RapidPlan module based on O-ring accelerator in volumetric modulated arc therapy for cervical cancer[J].Chinese Journal of Radiological Medicine and Protection,2022,42(9):691-696 |
The application of the RapidPlan module based on O-ring accelerator in volumetric modulated arc therapy for cervical cancer |
Received:June 20, 2022 |
DOI:10.3760/cma.j.cn112271-20220620-00259 |
KeyWords:O-ring linac RapidPlan automatic plan Cervical cancer Volumetric modulated arc therapy Consistency |
FundProject:“十三五”国家重点研发计划项目(2016YFC0105206,2016YFC0105207) |
Author Name | Affiliation | E-mail | Zhou Zhen | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China | | Yang Bo | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China | | Wang Zhiqun | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China | | Zhu Heling | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China | | Meng Xiangyin | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China | | Dong Tingting | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China | | Qiu Jie | Department of Radiation Oncology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing 100730, China | qj_ww@139.com |
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Abstract:: |
Objective To study the clinical feasibility and advantages of the RapidPlan module based on Halcyon 2.0 ring medical linear accelerator in the design of volumetric modulated arc therapy (VMAT) plans after cervical cancer surgery.Methods The data of 98 clinical cervical cancer cases were selected from the database,and VMAT artificial radiotherapy plans were designed based on Halcyon 2.0.Then,the designed plans were imported into the RapidPlan module to train the module for a prediction model with high goodness of fit.Another 20 patients after cervical cancer surgery were selected as the validation set to compare the differences in dosimetry,plan consistency,and plan execution efficiency between the manual plans and RapidPlan automatic plans.Results The RapidPlan automatic plans could obtain dose distribution of target volume and organs at risk with the same quality as the manual plans.The RapidPlan automatic plans provided slightly inferior protection of the femoral head but superior protection of the spinal cord compared to the manual plans,and the difference was statistically significant (t=4.71,P<0.001).The average MU of the RapidPlan automatic plans was 687.46,which was lower than that of the manual plan (815.34),and the difference was statistically significant (t=6.09,P< 0.05).The portal dosimetry (PD) verification revealed that the average γ passing rate (1 mm/1%) of the RapidPlan automatic plans was 89.48% and that of the manual plans was 88.22%,and the difference was statistically significant (t=3.35,P< 0.05).Conclusion RapidPlan automatic plans based on the Halcyon 2.0 platform can meet the clinical needs of the VMAT program for cervical cancer and has certain advantages. |
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