| Ding Shouliang,Liu Hongdong,Li Yongbao,Wang Bin,Huang Xiaoyan.Dosimetric effects of isocenter on intensity-modulated radiotherapy for MR-Linac[J].Chinese Journal of Radiological Medicine and Protection,2022,42(6):433-437 |
| Dosimetric effects of isocenter on intensity-modulated radiotherapy for MR-Linac |
| Received:January 26, 2022 |
| DOI：10.3760/cma.j.cn112271-20220126-00035 |
| KeyWords:MR-Linac Plan isocenter Plan evaluation Treatment plan design |
| FundProject:国家自然科学基金项目(11805292);广东省基础与应用基础研究粤穗联合基金青年项目(No. 2021A1515110642);中华国际医学交流基金会肿瘤精准放疗星火计划临床科研基金项目(HDRS2020030205);广州市益路同行慈善基金会肿瘤精准放疗登峰计划科研项目(2021-DF-009) |
| Author Name | Affiliation | E-mail | | Ding Shouliang | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Liu Hongdong | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Li Yongbao | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Wang Bin | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Huang Xiaoyan | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | huangxiaoy@sysucc.org.cn |
|
| Hits: 1597 |
| Download times: 531 |
| Abstract:: |
| Objective To analyze the dosimetric effects on off-center tumour treatment plan resulting from the MR-Linac-based isocenter position radiotherapy plan.Methods The cases of 19 patients who were treated in Sun Yat-sen University Cancer Center in 2020 were collected in this study. Two different IMRT plans were designed for each patient with off-center tumor both for group A with planned isocenter position as IMRT and group B with planed target center position as geometric center. The conformity index and homogeneity index of target, the dose normal tissue and the number of MU were compared between two plans.Results The two IMRT plans met clinical dosimetric requirements. No statistical differences were found both in homogeneity index and conformity index (P > 0.05). Also there was no differences found in doses to normal tissues. However, the MU number (1 149±903, t=2.804, P=0.012) in group A was higher than that in group B (970±652).Conclusions It is feasible to perform MR-Linac-based off-center treatment plan. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
