| Lian Dexing,Kou Shanshan,Lu Jianfei,Chao Jun,Zhu Zaiyun,Zhang Qingzhao,Hou Changsong.Measurement and analysis of 90Y radioactivity in urine of patients treated with 90Y resin microspheres[J].Chinese Journal of Radiological Medicine and Protection,2022,42(6):460-463 |
| Measurement and analysis of 90Y radioactivity in urine of patients treated with 90Y resin microspheres |
| Received:March 28, 2022 |
| DOI：10.3760/cma.j.cn112271-20220328-00125 |
| KeyWords:90Y resin microspheres Urinary excretion Radioactivity |
| FundProject: |
| Author Name | Affiliation | E-mail | | Lian Dexing | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Kou Shanshan | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Lu Jianfei | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Chao Jun | Hainan Center for Disease Control and Prevention, Haikou 570203, China | | | Zhu Zaiyun | Hainan Center for Disease Control and Prevention, Haikou 570203, China | | | Zhang Qingzhao | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Hou Changsong | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | houchangsong@nirp.chinacdc.cn |
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| Abstract:: |
| Objective To evaluate 90Y activity concentration in renal excretions during the first 48 hours after being treated with 90Y resin microspheres seleceive internal radiation therapy(SIRI) and to provide advice on the management of patient excreta after surgery.Methods After surgery, urine excreted from 3 patients during 0-24 h and 24-48 h was collected respectively, and the 90Y activity concentration in urine was tested and analyzed.Results 90Y radioctivity in the urine excreted from 3 patients after surgery was (1 266±258)kBq/GBq during 0-24 h and (140±106) kBq/GBq during 24-48 h, respectively, and 90Y activity concentration were (640±113) kBq/L during 0-24 h and (53±12) kBq/L during 24-48 h.Conclusions 90Y radioactivity in patient′s urine excreted at 1 d was about 10 times higher than that at 2 d. After surgery, patients can accelerate the reduction of free 90Y activity by increasing excretion. Urine excreted by the patients during hospitalization should be handled in accordance with the requirements of the national standard HJ 1188-2021 Radiation protection and safety requirements for nuclear medicine. |
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