Li Jianmin,Pang Linbin,Ying Chengdi,et al.Clinical study on individual protection after 125I seed implantation for abdominal and pelvic tumors[J].Chinese Journal of Radiological Medicine and Protection,2021,41(12):946-950 |
Clinical study on individual protection after 125I seed implantation for abdominal and pelvic tumors |
Received:March 18, 2021 |
DOI:10.3760/cma.j.issn.0254-5098.2021.12.012 |
KeyWords:125I seed Radiation dose rate Effective dose Individual protection |
FundProject:国家重点研发计划(2019YFE0120100) |
Author Name | Affiliation | E-mail | Li Jianmin | Department of Oncology, Dezhou People's Hospital, Dezhou 253012, China | | Pang Linbin | Department of Vascular Surgery, Dezhou People's Hospital, Dezhou 253012, China | | Ying Chengdi | Department of Oncology, Dezhou People's Hospital, Dezhou 253012, China | | Chen Guohua | Department of Oncology, Dezhou People's Hospital, Dezhou 253012, China | | Xia Haishui | Department of Oncology, Cangzhou People's Hospital, Cangzhou 061000, China | | Yang Xin | Department of Oncology, Dezhou People's Hospital, Dezhou 253012, China | | Meng Qi | Department of Oncology, Dezhou People's Hospital, Dezhou 253012, China | | Sui Aixia | Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China | | Wang Juan | Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China | | Zhang Hongtao | Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China | lizizhiru@163.com |
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Abstract:: |
Objective To study the radiation dose rate and effective dose in ambient environment due to 125I seed implantation in the treatment of the patients suffering abdominal and pelvic tumors, so as to provide reference for occupational protection of different groups. Methods Within 24 hours after operation, the radiation dose rate to 42 patients with abdominal and pelvic tumor with 125I seed implantation was monitored by using pocket dosimeter. The relationships between the total activity in the implanted particles and the measured dose rate, as well as between the implanted depth and the dose rate under the standard activity, were obtained by curve fitting. According to the formula, the relationship between the dose rate and the warning time was calculated. Results The dose rates at 30 cm, 50 cm and 100 cm of vertical particle implantation site were (6.92±2.87), (4.10±1.62) and (1.30±0.48) μSv/h, respectively (χ2=73.71, P<0.05). The dose rates on the left and right sides were (0.378±0.156) and (0.384±0.153) μSv/h at 30 cm, (0.170±0.089) and (0.17±0.086) μSv/h at 50 cm, (0.039 ±0.014) and (0.043±0.017) μSv/h at 100 cm, respectively (χ2=76.19, 76.33, P<0.05). There was a linear relationship between the dose rate at the vertical particle implantation site and the total activity in the implanted particles, and between the dose rate and the implantation depth under the standard activity. The relationship between the warning time and the dose rate to adults in the same bed, co-workers, minors in the same bed and pregnant women were as follows: t (d)=-106.616+83.779lnD(t), t (d)=26.556+ 85.933lnD (t), t(d)=3.088+85.017lnD(t). Conclusions After125I seed implantation, the radiation dose in the ambient environment is low, ensuring the radiation safety; and the measured dose rate decreases with the decrease in the total activity in the implanted particle and the increase in the implantation depth; at the same time, the warning time for different groups is calculated according to the measured dose rate or the total activity in the implanted particle and the depth of the implanted particle, so as to carry out individualized protection. |
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