| Yang Chenglin,Li Jianbin,Wang Wei.Sequence selection of postoperative radiotherapy and systemic treatment for breast cancer patients[J].Chinese Journal of Radiological Medicine and Protection,2021,41(10):790-795 |
| Sequence selection of postoperative radiotherapy and systemic treatment for breast cancer patients |
| Received:March 17, 2021 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.10.012 |
| KeyWords:Breast cancer Postoperative radiotherapy Postoperative systemic therapy Sequence selection |
| FundProject:山东省自然科学基金（ZR2020QH260）；国家自然科学基金青年基金（81703038） |
| Author Name | Affiliation | E-mail | | Yang Chenglin | Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China | | | Li Jianbin | Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan 250117, China | | | Wang Wei | Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, Tianjin's Clinical Research Center for Cancer, Tianjin 300070, China | w.wei1103@163.com |
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| Abstract:: |
| The role of postoperative adjuvant therapy is crucial for breast cancer. Also, there is no doubt that the combination of effective postoperative radiotherapy and adjuvant systemic therapy can not only reduce the local recurrence rate, but also improve the survival rate of patients. Although the timing of postoperative radiotherapy and part of systemic therapy is clear, some part of treatment regimens still remain elusive. In particular, the safety of concurrent therapy of postoperative consolidation chemotherapy and postoperative radiotherapy in patients with neoadjuvant chemotherapy, the safety of concurrent therapy of postoperative dual-targeted therapy and postoperative radiotherapy in HER2-positive patients, and the safety of simultaneous radiotherapy of small molecule inhibitors need to be further clarified. This article reviews the related papers on the sequence selection of postoperative radiotherapy and postoperative adjuvant systemic therapy for breast cancer. |
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