Li Taosheng,Li Wenyi,Lu Tingting,Xu Zhao.Current status of of nanodosimetry[J].Chinese Journal of Radiological Medicine and Protection,2021,41(10):784-789 |
Current status of of nanodosimetry |
Received:December 21, 2020 |
DOI:10.3760/cma.j.issn.0254-5098.2021.10.011 |
KeyWords:Nanodosimetry Ionizing cluster size Probability distribution of ionizing cluster Nanodosimeter |
FundProject:国家重点研发计划资助(2020YFB1901900) |
Author Name | Affiliation | E-mail | Li Taosheng | Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei 230031, China | | Li Wenyi | Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei 230031, China | | Lu Tingting | Anhui University of Traditional Chinese Medicine, Hefei 230012, China | | Xu Zhao | Key Laboratory of Neutronics and Radiation Safety, Institute of Nuclear Energy Safety Technology, Chinese Academy of Sciences, Hefei 230031, China | zhao.xu@inest.cas.cn |
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Abstract:: |
Nanodosimetry, a new discipline developed on the basis of microdosimetry, is based on the structural characteristics of particle tracks and studies on the probability distribution of ionization pairs in a specific volume to characterize the damage degree of DNA strand. Now nanodosimetric quantities, which may be measured, gradually form the concept such as ionization cluster size, ionizing cluster size distribution and complementary cumulative probability distribution etc. This paper aims to establish and explain the relationship between nanodosimetry and DNA damage and repair. On the basis of reviewing the current measurement and calculation method of nanodosimetry, this paper summarized the development trend and application prospect of nanodosimetry, and put forward the future research direction of nanodosimetry. |
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