| Nie Zhuang,Lei Ziqiao,Yang Ming,Yu Jianming.Estimating organ dose and specific effective dose in coronary artery CT angiography based on size-specific dose estimation[J].Chinese Journal of Radiological Medicine and Protection,2021,41(10):778-783 |
| Estimating organ dose and specific effective dose in coronary artery CT angiography based on size-specific dose estimation |
| Received:May 08, 2021 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.10.010 |
| KeyWords:Size-specific dose estimation CT angiography Coronary artery Organ dose Specific effective dose |
| FundProject:国家重点研发计划资助（2020YFB1901900） |
| Author Name | Affiliation | E-mail | | Nie Zhuang | Department of Radiology, Union Hospital of Tongji Medical College of Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Lei Ziqiao | Department of Radiology, Union Hospital of Tongji Medical College of Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | leiziqiaowhxh@163.com | | Yang Ming | Department of Radiology, Union Hospital of Tongji Medical College of Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Yu Jianming | Department of Radiology, Union Hospital of Tongji Medical College of Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | |
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| Abstract:: |
| Objective To study the feasibility that using size-specific dose estimation (SSDE) to estimate organ dose and effective dose in coronary CT angiography (CTA). Methods Totally 421 consecutive patients with coronary artery CTA were included and retrospectively analized. All patients were scanned using the 3rd generation dual-source Force CT with prospectively ECG gated axis scan mode. The size specific dose estimation(SSDE) for each patient was conducted by calculate water equivalent diameters with Radimetrics. The organ doses of heart, lung, liver and breast, were estimated with Monte Carlo method. Patient-specific effective dose was calculated as a weighted sum of simulated organ doses with the coefficients from ICRP 103. Linear correlation analysis was used to validate the relationship between SSDE and organ doses as well as effective dose, and to derive coefficients for patient specific dose estimation. The mean error rate was used to evaluate estimation accuracy. Results The CTDIvol, SSDE and effective dose were (16.8±8.7)mGy, (20.8±8.8)mGy and (4.4±2.9)mSv, respectively. The linear fitting formula for estimating organ dose based on SSDE were:Y=1.2X-6.4 (R2=0.91, P<0.05, mean error 0.1%) for heart, Y=1.4X-7.4 (R2=0.91, P<0.05, mean error 7.9%) for breast, Y=0.89X-4.6 (R2=0.86, P<0.05, mean error 8.3%) for lung, and Y=0.36X-1.8 (R2=0.64, P<0.05, mean error -17.9%) for liver. The linear fitting formula for estimating the individual effective dose based on SSDE were:Y=0.21X-1.2 (R2=0.92, P<0.05, mean error 0.2%) for men, Y=0.39X-2.2 (R2=0.93, P<0.05, mean error 1.7%) for women. Conclusions In coronary artery CTA, the absorbed dose of the organs and patient specific effective dose could be estimated with SSDE and the corresponding conversion coefficients, which will help to achieve personalized assessment and precise management of patient radiation dose and risk in clinical practice. |
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