| Yin Yaru,Yang Luxun,Liu Jing,Lu Binghui,Li Rong.Research progress in the application of exosomes in radiological medicine and underlying mechanisms[J].Chinese Journal of Radiological Medicine and Protection,2021,41(7):547-551 |
| Research progress in the application of exosomes in radiological medicine and underlying mechanisms |
| Received:February 05, 2021 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.07.014 |
| KeyWords:Exosomes Radiation Bystander effect Radiation injury Tumor |
| FundProject:国家自然科学基金（81773364）；四川省自然基金重点项目（2017SZ0004）；全军后勤科研重大项目（AWS17J007） |
| Author Name | Affiliation | E-mail | | Yin Yaru | Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Military Key Laboratory of Nanomedicine, Department of Military Preventive Medicine, Army Medical University, Chongqing 400038, China | | | Yang Luxun | Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Military Key Laboratory of Nanomedicine, Department of Military Preventive Medicine, Army Medical University, Chongqing 400038, China | | | Liu Jing | Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Military Key Laboratory of Nanomedicine, Department of Military Preventive Medicine, Army Medical University, Chongqing 400038, China | | | Lu Binghui | Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Military Key Laboratory of Nanomedicine, Department of Military Preventive Medicine, Army Medical University, Chongqing 400038, China | | | Li Rong | Institute of Combined Injury, State Key Laboratory of Trauma, Burns and Combined Injury, Military Key Laboratory of Nanomedicine, Department of Military Preventive Medicine, Army Medical University, Chongqing 400038, China | lirongyl@sina.com |
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| Abstract:: |
| Nuclear energy is widely used in various fields such as military, medicine, scientific research, industry and agriculture.Nuclear accident may lead to radiation damage to the bodyofpractitioners. At present, the treatment of severe bone marrow radiation sickness is still not ideal.Exosomes are small vesicles with a size of 30-130 nm secreted by living cells and carry a variety of active substances including protein, RNA, DNA, which isimportant medium of intercellular communication.The contents of exosomes can be used not only as biomarkers of radiation damage, but also for the treatment of radiation damage. This article reviewsthe research progress of the application of exosomes in radiological medicine and underlying mechanisms. |
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