| Ding Shouliang,Liu Hongdong,Wang Bin,Li Yongbao,Liu Biaoshui,Xia Yunfei,Huang Xiaoyan,Wu Dehua.Dose evaluation of adaptive radiotherapy using high-field MR-Linac systems for head and neck cancers[J].Chinese Journal of Radiological Medicine and Protection,2021,41(7):499-503 |
| Dose evaluation of adaptive radiotherapy using high-field MR-Linac systems for head and neck cancers |
| Received:November 05, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.07.004 |
| KeyWords:MR-Linac Adaptive plan Dose evaluation |
| FundProject:国家自然科学基金项目（11805292）；广东省自然科学基金项目（2018A0303100020） |
| Author Name | Affiliation | E-mail | | Ding Shouliang | Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China | | | Liu Hongdong | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Wang Bin | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Li Yongbao | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Liu Biaoshui | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Xia Yunfei | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Huang Xiaoyan | Department of Radiation Oncology, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China | | | Wu Dehua | Department of Radiation Oncology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China | 18602062748@163.com |
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| Abstract:: |
| Objective To investigate the feasibilityof the adaptive radiotherapy using high-field MR-Linac systems for head neck cancers and perform the evaluation of target coverage and dose criteria. Methods This study investigated 128 treatment plans of six patients who were treated on 1.5T MR-Linacsystems in Sun Yat-sen University Cancer Center in 2019, compared the differences in target coverage and dose criteria between the dose accumulation in the adaptive radiotherapy using MR-Linac systems and the reference plans, and evaluated the target coverage and dose criteria of each fraction of adaptive plan based on daily MRI anatomy. Results There was no significant change in the target coverage and dose criteria for each treatment fraction(<1%). However, the change of lens dose was significant (maximum 98%). In addition, the result showed that there was no significant difference in target coverage and dose criteria between the dose accumulation in adaptive radiotherapy using MR-Linac systems and reference plans.In contrast, the average dose to lens was increased by 31.7%. Conclusions It is feasible to perform adaptive radiotherapy using 1.5T MR-Linacsystems for head neck cancers according tothe evaluation of target coverage and dose criteria. Additionally, since the actual dose tolens was quite different from the reference plan, the lens exposure should be considered in clinical practice. |
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