| Liao Zhiyun,Wu Bian,Yang Kunyu.Current treatment of juvenile nasopharyngeal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2021,41(5):390-395 |
| Current treatment of juvenile nasopharyngeal carcinoma |
| Received:August 20, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.05.013 |
| KeyWords:Adolescent Nasopharyngeal carcinoma Induction chemotherapy Radiotherapy Immunotherapy |
| FundProject:国家自然科学基金（81874222） |
| Author Name | Affiliation | E-mail | | Liao Zhiyun | Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China | | | Wu Bian | Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China | bianwu@hust.edu.cn | | Yang Kunyu | Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China | |
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| Abstract:: |
| Nasopharyngeal carcinoma (NPC) is a cancer arising from the nasopharynx epithelium, and is one of the most frequent head and neck malignancies in adolescents. Treatment strategies for juvenile NPC follow the guidelines established for adult NPC. However, juvenile NPC has its distinct clinical characteristics. For juvenile patients in the developmental stage, the late toxicity of treatment should not be ignored. Therefore, it is important to seek appropriate treatment strategies for juvenile NPC. This review gives an overview of the epidemiology, clinical characteristics and current treatment of juvenile NPC, along with the promising strategies to reduce the intensity of treatment in adolescents. This review aims to provide new insight for improving the treatment of this disease. |
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