| Luo Hui,Ge Hong,Nie Wenna,Liu Hui,Hu Yamei,Xu Wenjuan,Deng Guodong.Application of low dose radiation therapy in the treatment of COVID-19 pneumonia[J].Chinese Journal of Radiological Medicine and Protection,2021,41(2):151-154 |
| Application of low dose radiation therapy in the treatment of COVID-19 pneumonia |
| Received:September 08, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.02.013 |
| KeyWords:Low dose radiation therapy COVID-19 pneumonia Anti-inflammatory effect |
| FundProject:国家自然科学基金（81773230） |
| Author Name | Affiliation | E-mail | | Luo Hui | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Ge Hong | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | progh@gs.zzu.edu.cn | | Nie Wenna | China-US(Henan) Hormel Cancer Institute, Zhengzhou 450003, China | | | Liu Hui | China-US(Henan) Hormel Cancer Institute, Zhengzhou 450003, China | | | Hu Yamei | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Xu Wenjuan | Department of Respiratory and Critical Care Medicine, Zhongnan Hospital Wuhan University, Wuhan 430071, China | | | Deng Guodong | Department of Etiology and Carcinogenesis, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China | |
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| Abstract:: |
| With the global pandemic of COVID-19, cytokine storms in critical patients with pneumonia is really a problem and need to be solved immediately.Low dose radiation therapy (LDRT) has been temporarily used to treat pneumonia.In the past decades, researchers were dedicated to clarify the biological mechanism of LDRT.LDRT plays a unique role in the suppression of inflammation, preliminary outcomes have been acquired in critical patients with COVID-19 pneumonia, and radiotherapy community is paying attention to this treatment strategy.This review summarizes the application of LDRT in pneumonia, its biological mechanism, the result of LDRT in COVID-19 pneumonia, the existing problems and prospective in clinic. |
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