| Cheng Bo,Fang Shijie,Ren Qiang,et al.Study on the clinical application of the fast direct aperture optimization of DeepPlan treatment planning system[J].Chinese Journal of Radiological Medicine and Protection,2020,40(12):938-944 |
| Study on the clinical application of the fast direct aperture optimization of DeepPlan treatment planning system |
| Received:April 03, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2020.12.008 |
| KeyWords:DeepPlan Pinnacle Direct aperture optimization Intensity modulated radiation therapy |
| FundProject:安徽省自然科学基金（1908085MA27）；安徽省重点研究与开发计划项目（1804a09020039） |
| Author Name | Affiliation | E-mail | | Cheng Bo | School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230025, China | | | Fang Shijie | School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230025, China | | | Ren Qiang | Anhui Wisedom Technology Co. Ltd, Hefei 230088, China | | | Zhou Jieping | Department of Radiation Oncology, Anhui Provincial Cancer Hospital, Hefei 230031, China | | | Cao Ruifen | School of Computer Science and Engineering, Anhui University, Hefei 230601, China | | | Wu Aidong | Deptartment of Radiotherapy, the First Affiliated Hospital of USTC, Hefei 230031, China | | | George Xu | School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230025, China | | | Pei Xi | School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230025, China | xpei@ustc.edu.cn |
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| Abstract:: |
| Objective To assess the clinical application of fast direct aperture optimization in self-developed DeepPlan treatment planning system, by comparing with the Pinnacle system in the clinical static IMRT cases. Methods Totally 25 clinical cases from Anhui Provincial Cancer Hospital were selected to get the static IMRT plan by DeepPlan and Pinnacle system, including 6 cases of head and neck cancer, 10 cases of chest and abdomen cancer and 9 cases of pelvis cancer. Then we compared the two groups of plans in terms of comformity and homogeneity, segment number and monitor unit. Finally, we compared the dosimetric parameters of cervical cancer cases in two systems. Results All of the cases in the two systems could satisfy the clinical dose requirements. The mean optimization time and the mean calculation time in DeepPlan were 86 s and 8.36 s, respectively. Compared with Pinnacle system, DeepPlan had less monitor unit, higher conformity index and higher number of apertures, with the significant statisical difference (t=-3.208, 2.912, 2.875, P<0.05). And there was no statistical difference in homogeneity index between DeepPlan and Pinnacle (P>0.05). For cervical cancer cases, the V40 of bladder was significantly higher (t=-5.498, P<0.05) and the V20 of small intestine was significantly lower (t=2.581, P<0.05) in DeepPlan system, compared to Pinnacle system. Conclusions With the graphics processing unit acceleration, the optimization method in DeepPlan system can produce efficient plans in a short time, which can satisfy the clinical requirement. Compared with Pinnacle system, the plan of DeepPlan system has better comfomity and less monitor units, but higher number of aperture. For cervical cancer, DeepPlan has more effective protection for bladder and less effective protection for small intestine. |
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