| Zhang Ruidan,Yang Lili,Sun Quanfu,Pang Lijuan,Gao Lihui.Diagnosis of a case of occupational exposure skin cancer and identification of labor ability[J].Chinese Journal of Radiological Medicine and Protection,2020,40(7):540-542 |
| Diagnosis of a case of occupational exposure skin cancer and identification of labor ability |
| Received:January 19, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2020.07.009 |
| KeyWords:Ionizing radiation Medical protection Free radicals DNA oxidative damage |
| FundProject:国家自然科学基金（81803173）；江苏省自然科学基金（BK20180131） |
| Author Name | Affiliation | E-mail | | Zhang Ruidan | Shijiazhuang Hospital for Occupational Disease Prevention, Shijiazhuang 050031, China | | | Yang Lili | Shijiazhuang Hospital for Occupational Disease Prevention, Shijiazhuang 050031, China | | | Sun Quanfu | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | sunquanfu@nirp.chinacdc.cn | | Pang Lijuan | Shijiazhuang Hospital for Occupational Disease Prevention, Shijiazhuang 050031, China | | | Gao Lihui | Shijiazhuang Hospital for Occupational Disease Prevention, Shijiazhuang 050031, China | |
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| Abstract:: |
| Nowadays, ionizing radiation has become one of the threaten factors for human healthy. Exploring effective protective strategies is an important topic in radiological medicine. Timely using of the radiation protection agents is the most direct and effective medical protective strategy for reducing the damage of ionizing radiation to normal tissues of the body. A large number of new radiation protective agents based on mechanisms such as scavenging of free radicals, promoting DNA damage repair, inducing hypoxia of irradiated tissues and blocking bystander effect have been developed gradually. This review summarizes a variety of radiation protective agents, and their potential molecular biological mechanisms reported in recent years, to provide theoretical reference for exploring novel medical protective agents of ionizing radiation. |
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