| Sun Fenghao,Xing Ligang.Adverse events of radiotherapy combined with immune checkpoint inhibitors[J].Chinese Journal of Radiological Medicine and Protection,2019,39(8):594-598 |
| Adverse events of radiotherapy combined with immune checkpoint inhibitors |
| Received:April 02, 2019 |
| DOI：10.3760/cma.j.issn.0254-5098.2019.08.006 |
| KeyWords:Radiation therapy Immune checkpoint inhibitors Adverse events |
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| Abstract:: |
| Radiation therapy and immune checkpoint inhibitors(ICI) have a synergistic effect on anti-tumor, which involves a series of complex mechanisms of effects with the immune system, and can improve the clinical outcomes of cancer patients. However, the mechanism by which radiation therapy combined with ICI synergistically modulates the immune response may also trigger treatment-related adverse events. In view of the increasing number of clinical studies and practices of combination therapy, it is necessary to pay attention to the risk of adverse events in combination therapy of radiotherapy and ICI, so as to evaluate the safety of combination therapy. |
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