| Xu Jian,He Xiaolong,Fang Huanxin,Wang Xiangquan,Mao Dewang.Comparative analysis of size-specific dose estimates in coronary computed tomography angiography[J].Chinese Journal of Radiological Medicine and Protection,2019,39(7):523-528 |
| Comparative analysis of size-specific dose estimates in coronary computed tomography angiography |
| Received:March 21, 2019 |
| DOI：10.3760/cma.j.issn.0254-5098.2019.07.008 |
| KeyWords:Coronary vessels Tomography, X-ray Size-specific Dose estimation |
| FundProject: |
| Author Name | Affiliation | E-mail | | Xu Jian | Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China | | | He Xiaolong | Department of Radiology, Quzhou People's Hospital, Quzhou 324000, China | | | Fang Huanxin | Department of Radiology, Quzhou People's Hospital, Quzhou 324000, China | | | Wang Xiangquan | Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China | | | Mao Dewang | Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China | zjhzmdw@sina.com |
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| Abstract:: |
| Objective To investigate the difference of size-specific dose estimates (SSDEs) based on effective diameter (deff) and water equivalent diameter (dw) in coronary computed tomography angiography (CCTA) and explore the causes. Methods A total of 99 patients undergoing CCTA were enrolled in this retrospective study. SSDEs (SSDEdeff and SSDEdw) were calculated in two approaches using deff and dw, respectively. Mean absolute relative difference (MARD) was computed as an index to quantify the consistency of SSDEdeff and SSDEdw. Multivariate stepwise regression analysis was performed to study the factors influencing MARD. Results The values deff and dw were positively correlated with body mass index (BMI) (r=0.869, 0.823, P<0.05). The median (interquartile range) of SSDEdeff and SSDEdw were 12.34(11.75, 12.98) mGy, 13.78(13.02, 15.04) mGy, respectively. SSDEdeff was lower by 10.45% than SSDEdw (Z=-8.186, P<0.05). Both SSDEdeff and SSDEdw were negatively correlated with BMI and dw (r=-0.765, -0.680, -0.701, -0.840, P<0.05). MARD of SSDEdeff and SSDEdw was generally at 11.39%. No statistical significance was found in the correlation of MARD with BMI (r=0.031, P>0.05), however, positive correlation was shown between MARD and deff (r=0.251, P<0.05), but negative correlation for MARD and dw (r=-0.379, P<0.05). With respect to the factors influencing MARD, four variables were included into the regression equation. MARD was positively correlated with the area of both air-filled lungs (Arealow) and soft tissues (Areasoft) (β=0.634, 0.102, P<0.05), and negatively correlated with the area of bone, enhanced cardiac chambers and aorta (Areahigh) and the CT value of air-filled lungs (SIlow) (β=-0.234, -0.343, P<0.05). Conclusions SSDEdeff was approximately 10.45% lower than SSDEdw, which was predominantly influenced by the area of air-filled lungs due to the characteristics of low X-ray attenuation in CCTA. |
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