Hu Qiaoqiao,Jiang Fan,Wang Meijiao,Zhang Yibao,Yao Kaining,Gong Jian,Wu Hao,Yue Haizhen.A comparative study of dosimetric verification of HalcyonTM treatment plans using Varian Portal Dosimetry and PTW array 1500[J].Chinese Journal of Radiological Medicine and Protection,2019,39(1):58-62
A comparative study of dosimetric verification of HalcyonTM treatment plans using Varian Portal Dosimetry and PTW array 1500
Received:June 06, 2018  
DOI:10.3760/cma.j.issn.0254-5098.2019.01.011
KeyWords:HalcyonTM accelerator  Dose  γ 2D analysis  Electronic portal imaging device
FundProject:北京市自然科学基金(1174016、7172048、1184014);首都卫生发展科研专项(首发2018-4-1027);四川省科技厅项目(2018HH0099)
Author NameAffiliationE-mail
Hu Qiaoqiao Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China  
Jiang Fan Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China  
Wang Meijiao Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China  
Zhang Yibao Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China  
Yao Kaining Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China  
Gong Jian Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China  
Wu Hao Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China  
Yue Haizhen Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Department of Radiotherapy, Peking University Cancer Hospital & Institute, Beijing 100142, China yuehzh@163.com 
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Abstract::
      Objective To compare two pretreatment plan QA methods for HalcyonTM accelerator using Portal Dosimetry (PD), and PTW OCTAVIUS 1500 detector array + Octagonal phantom (Oct 1500) respectively.Methods Parallel measurement-based pretreatment QA using two methods was performed for 22 IMRT/VMAT plans (74 fields) that have been used to treat 20 patients recruited in the Halcyon clinical trial. Several γ 2D comparisons were also applied to provide guidelines for Halcyon planning QA.Results Using Oct1500 method, the γ 2D passing rates for 74 fields in 22 Plans were 95.26±3.59, 95.01±3.62 (Local Dose), 99.05±1.35, 98.57±1.96 (Max Dose) respectively. Two-related samples non-parametric tests suggested that the differences between the evaluation criteria were of statistical significance (Z=-7.220, -4.108, P<0.05). For PD method, the γ 2D passing rates were 84.11%±1.35% (1 mm/1%), 99.07%±1.35% (2 mm/2%), and 99.86%±1.35% (3 mm/3%). Two-related samples non-parametric tests suggested that the differences between evaluation criteria of PD method were statistically significant (Z=-7.475, -7.475, -6.906, P<0.05). For 74 fields and max dose, 3 mm/3% evaluation criteria, two-related samples non-parametric tests suggested that the differences between PD and Oct1500 method were statistically significant (Z=-5.072, P<0.05).Conclusions Both methods can be used for Halcyon pretreatment plan QA. PD is superior to Oct1500 with respect to efficiency and spatial resolution-induced verification accuracy. The criteria of 2 mm/2% for PD, and Max Dose/3 mm/3% for Oct1500 was suggested.
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