Wu Ailin,Wu Aidong,Zhu Lei,et al.Monte Carlo simulation study of dosimetric parameters of Varian HDR 192Ir source[J].Chinese Journal of Radiological Medicine and Protection,2018,38(11):859-864
Monte Carlo simulation study of dosimetric parameters of Varian HDR 192Ir source
Received:February 06, 2018  
DOI:10.3760/cma.j.issn.0254-5098.2018.11.012
KeyWords:Brachytherapy  192Ir source  Monte Carlo simulation  Dosimetric parameters
FundProject:国家自然科学基金项目(11805198)
Author NameAffiliationE-mail
Wu Ailin Tumor Radiotherapy Room, The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei 230031, China  
Wu Aidong Tumor Radiotherapy Room, The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei 230031, China aidongwu@21cn.com 
Zhu Lei School of Physical Sciences, University of Science and Technology of China, Hefei 230026, China  
Liu Yunqin Tumor Radiotherapy Room, The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei 230031, China  
Qian Liting Tumor Radiotherapy Room, The First Affiliated Hospital of University of Science and Technology of China, Anhui Provincial Cancer Hospital, Hefei 230031, China  
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Abstract::
      Objective To study the dosimetric parameters of Varian GammaMed Plus HDR 192Ir source via Monte Carlo (MC) method based on the recommendation of the American Association of Physicist in Medicine (AAPM) and European Society for Radiotherapy and Oncology (ESTRO). Methods Using the Monte Carlo program EGSnrc, an accurate model of 192Ir source for MC calculations was establish firstly. Through formula derivation, bilinear interpolation and unit conversion, the air kerma strength per unit source activity, the dose rate constant, radial dose function and anisotropy function was obtained then, and compare the result with those in other published studies. Results The air kerma strength per unit source activity was 9.781×10-8 U/Bq. The dose rate constant was 1.113 cGy·h-1·U-1,with a discrepancy of less than 0.4% compared with result published in other works. Furthermore, the curves of radial dose function and anisotropy function overall agree with the data shown in the literature. Conclusions The feasibility of performing dosimetric studies of 192Ir source using the MC software EGSnrc was demonstrated. This work provides a theoretical guidance on analysis of the dose distribution of brachytherapy and on evaluation of the dose accuracy of clinical radiotherapy.
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