Tang Yin,Zhang Huojun.Research advances in tumor radiosensitization mediated by topoisomerase inhibitors[J].Chinese Journal of Radiological Medicine and Protection,2018,38(6):466-470 |
Research advances in tumor radiosensitization mediated by topoisomerase inhibitors |
Received:October 16, 2017 |
DOI:10.3760/cma.j.issn.0254-5098.2018.06.014 |
KeyWords:Topoisomerase inhibitors Radiotherapy Radiosensitization |
FundProject:中国健康促进基金会项目(THC2015001) |
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Abstract:: |
As anticancer drugs, topoisomerase inhibitors have been widely used in clinical practice, and their radiosensitivity has been gradually recognized. Many topoisomerase inhibitors are currently in pre-clinical and clinical studies. Several studies have shown that some topoisomerase inhibitors may be potential ideal radiosensitizers. However, the physico-chemical properties, toxicity and sensitization effects should be further investigated. |
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