Xu Fei,Guo Fuxin,Peng Ran,Fan Jinghong,Li Weiyan,Zhang Xile,Wang Wei,Cheng Cheng,Zhao Tiandi,Wang Junjie.Analysis of the qualified rate of the fiducial markers and the cause of unqualified ones by the means of 3D-printing co-planar template assisted CT-guided implantation in stereotactic body radiation therapy of CyberKnife[J].Chinese Journal of Radiological Medicine and Protection,2018,38(3):187-191
Analysis of the qualified rate of the fiducial markers and the cause of unqualified ones by the means of 3D-printing co-planar template assisted CT-guided implantation in stereotactic body radiation therapy of CyberKnife
Received:January 22, 2018  
DOI:10.3760/cma.j.issn.0254-5098.2018.03.005
KeyWords:Tumor  CyberKnife  Fiducial markers  Qualified rate  3D-printing co-planar template
FundProject:福建省自然科学基金项目(2015J01366);福建省卫生计生委创新课题(2014-CXB-5)
Author NameAffiliationE-mail
Xu Fei Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Guo Fuxin Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Peng Ran Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Fan Jinghong Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Li Weiyan Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Zhang Xile Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Wang Wei Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Cheng Cheng Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Zhao Tiandi Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Wang Junjie Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China junjiewang_edu@sina.cn 
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Abstract::
      Objective To analyze the qualified rate of the fiducial markers during 3D-printing co-planar template assisted CT-guided implantation in stereotactic body radiation therapy by CyberKnife,and to explore the cause of the unavailable markers in order to provide the reference for the fiducial implantation, treatment planning and radiotherapy delivery. Methods From March to December 2017, a total of 52 cases were planned to stereotactic body radiation therapy(SBRT) using CyberKnife by fiducial tracking, and the fiducial markers were implanted based on CT-guided 3D-printing co-planar template, including 22 in lung, 12 in liver, 5 in mediastinal lymph node, 8 in retroperitoneal lymph node, 3 in pancreas, each in celiac and pelvic lymph nodes, respectively. Except 7 cases not fit for CyberKnife treatment, 45 cases finished the treatment of CyberKnife, but there were 3 cases changed to spine tracking due to unqualified fiducial markers. The number of fiducial markers used and the qualified rate of fiducial markers were analyzed,and the cause of unqualified fiducial markers was studied.Results A total of 131 fiducial markers were impanted into 42 cases who finally received the treatment of CyberKnife by fiducial tracking,including 85 fiducial markers qualified(64.89%) and 46 fiducial markers unqualified (35.11%). The main causes of the unqualified fiducial markers varied, including outrange of rigidity error(26.08%), fiducial markers unavailable(41.31%), and other (32.61%).Conclusions The 3D-printing co-planar template assisted CT-guided implantation could reduce the number of puncture needles used,help to decrease the risk of puncture and trauma and the incidence of complications after the fiducial markers implantation. However, the fiducial markers implanted by this way would be abandoned by a variety of causes and should be taken into account before the fiducial markers implantation.
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