Jiang Chenxue,Gu Feiying,Xu Yaping.Research progress on the association between c-Met and radiosensitivity in esophageal cancer[J].Chinese Journal of Radiological Medicine and Protection,2017,37(12):962-964
Research progress on the association between c-Met and radiosensitivity in esophageal cancer
Received:May 11, 2017  
DOI:10.3760/cma.j.issn.0254-5098.2017.12.016
KeyWords:Esophageal cancer  c-Met  Radiosensitivity  Target therapy
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Author NameAffiliationE-mail
Jiang Chenxue Department of Radiation Oncology, Zhejiang Cancer Hosital, Hangzhou 310022, China  
Gu Feiying Department of Radiation Oncology, Zhejiang Cancer Hosital, Hangzhou 310022, China  
Xu Yaping Department of Radiation Oncology, Zhejiang Cancer Hosital, Hangzhou 310022, China xuyaping1207@163.com 
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Abstract::
      Esophageal cancer is a common gastrointestinal cancer in China with poor prognosis. Radiotherapy is the main treatment of esophageal cancer, and radiosensitivity of the tumor cell is a significant reason for the efficacy of radiotherapy. Mesenchymal-epithelial transition factor (c-Met) and its signaling pathway play an significant role in tumorigenesis, development, invasion, metastasis and treatment resistance. This review summarizes the association between expression of c-Met and radiosensitivity in esophageal cancer.
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