| Pan Tianfan,Lu Jian,Wang Yong,Guo Jinhe.Research progress of 125Ⅰ radioactive seed interstitial brachytherapy in the treatment for pelvic malignancies[J].Chinese Journal of Radiological Medicine and Protection,2017,37(7):557-561 |
| Research progress of 125Ⅰ radioactive seed interstitial brachytherapy in the treatment for pelvic malignancies |
| Received:April 26, 2017 |
| DOI：10.3760/cma.j.issn.0254-5098.2017.07.016 |
| KeyWords:125Ⅰ Brachytherapy Pelvic malignancies Radiation treatment planning Three dimensional printing |
| FundProject:国家自然科学基金（81471762）；江苏省省级重点研发专项资金（BE2016783） |
| Author Name | Affiliation | E-mail | | Pan Tianfan | Department of Interventional Radiology and Vascular Surgery, Zhongda Hospital, Medical School of Southeast University, Nanjing 210009, China | | | Lu Jian | Department of Interventional Radiology and Vascular Surgery, Zhongda Hospital, Medical School of Southeast University, Nanjing 210009, China | | | Wang Yong | Department of Interventional Radiology and Vascular Surgery, Zhongda Hospital, Medical School of Southeast University, Nanjing 210009, China | | | Guo Jinhe | Department of Interventional Radiology and Vascular Surgery, Zhongda Hospital, Medical School of Southeast University, Nanjing 210009, China | jinheguo@sina.com |
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| Abstract:: |
| Brachytherapy with 125Ⅰ radioactive seed has the advantages of low dose-rate,comtinuous irradiation and repeated implantation to inhibit the replication of tumor cells, and the repeatable implantation. It has been widely used in the treatment for cervial cancer, and can also be applied to pelvic malignancies, including ovarian cancer, colorectal cancer, bladder cancer. Compared with external beam radiotherapy, it can improve the dose of target region to control tumor effectively. At the same time,it can protect the normal tissues and reduce the occurrence of complications. In this paper, we summarized the specialty, function mechanism, complications and application status of radioactive 125Ⅰ seed interstitial implantation in the treatment of pelvic malignancies. The application of three dimensional printing in brachytherapy with radioactive 125Ⅰ seed was also introduced.This review can provide a reliable basis for future standardized seed implantation treatment for pelvic malignancies. |
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