Jiang Ping,Guo Fuxin,Jiang Yuliang,Ji Zhe,Peng Ran,Sun Haitao,Fan Jinghong,Li Xu,Li Weiyan,Wang Junjie.3D-printing non-coplanar template assisted CT-guided 125Ⅰ seed implantation on pelvic recurrent cervical cancer[J].Chinese Journal of Radiological Medicine and Protection,2017,37(7):490-494
3D-printing non-coplanar template assisted CT-guided 125Ⅰ seed implantation on pelvic recurrent cervical cancer
Received:February 28, 2017  
DOI:10.3760/cma.j.issn.0254-5098.2017.07.003
KeyWords:3D-printing non-coplanar tempalte  Cervical cancer  Seed implantation  Brachytherapy  Dosimetry
FundProject:首都临床特色应用研究与成果推广项目(Z151100004015171)
Author NameAffiliationE-mail
Jiang Ping Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Guo Fuxin Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Jiang Yuliang Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Ji Zhe Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Peng Ran Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Sun Haitao Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Fan Jinghong Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Li Xu Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Li Weiyan Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Wang Junjie Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China junjiewang_edu@sina.cn 
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Abstract::
      Objective To investigate the accuracy of 3D-printing non-coplanar template (3D-PNCT) assisted 125Ⅰ seed implantation with CT guidance in the pelvic recurrent cervical between the pre-plan and post-plan dosimetric parameters. Methods Nine patients with pelvic recurrent cervical cancer received 125Ⅰ seed implantation under CT guidance assisted with 3D-PNCT. A pre-plan based brachytherapy treatment planning system (B-TPS) assisted with 3D-PNCT for seed needle depth, direction and angle was designed. The dosimetry parameters including homogeneity index (HI), dose of 90% target volume (D90), mPD, volume percent of 100%, 150% and 200% prescribed dose V100, V150 and V200 and organ at risk between the pre-plan and post-plan were compared. Results Total seeds number was 675 (median 44, 25-114) according to pre-plan, and 669 (median 47, 25-113) seeds were implanted actually. 138 needles need implant according to preplan, and 132 needles was implanted actually. The median angle deviation was 1.99°±2.94°(0°-13°). There was no significant difference of HI, EI and CI between per-and post-plan. The differences of D90, MPD, V100, V150 and V200 between pre-and post-plan were not significant. Conclusions The confidence of pre-plan and post-plan for 3D-PNCT assisted 125Ⅰ seed implantation in the pelvic recurrent cervical cancer could be accurately performed under CT guidance.
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