| Zhou Chen,Liu Shuming,Shi Yan,Huang Mingwei,Zheng Lei,Lyu Xiaoming,Zhang Jie,Zhang Jianguo.Clinical analysis of 125I brachytherapy alone for 24 recurrent parotid gland carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2017,37(6):447-450 |
| Clinical analysis of 125I brachytherapy alone for 24 recurrent parotid gland carcinoma |
| Received:October 29, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2017.06.009 |
| KeyWords:Parotid gland carcinoma Recurrent carcinoma 125I seed Brachytherapy |
| FundProject:国家科技支撑计划项目（2014BAI12B04） |
| Author Name | Affiliation | E-mail | | Zhou Chen | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | | | Liu Shuming | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | | | Shi Yan | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | | | Huang Mingwei | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | | | Zheng Lei | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | | | Lyu Xiaoming | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | | | Zhang Jie | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | zhangjie06@126.com | | Zhang Jianguo | Department of Oral and Maxillofacial Surgery, Peking University Hospital of Stomatology, Beijing 100081, China | |
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| Abstract:: |
| Objective To evaluate the efficacy of 125I brachytherapy alone for the treatment of recurrent parotid gland carcinoma. Methods Recurrent parotid gland carcinoma patients (n=24) treated by 125I brachytherapy alone between 2006 and 2013 at Peking University Hospital of Stomatology were enrolled in this retrospective study.All patients underwent surgery or radiotherapy.The local control rate,survival rate,and side effects were evaluated. Results The median follow-up time was 21 months (range,4-59 months).Among the 24 patients,6 had local failure and 10 died during the follow-up period.The 1-and 3-year overall survival rates,progression-free survival rates,local control rates were 74.8% and 39.3%,74.8% and 31.5%,82.0% and 69.4%,respectively.No grade 3 or over radiation injury was found. Conclusions 125I seed brachytherapy alone could provide an alternative treatment method for inoperable recurrent parotid gland carcinoma patients. |
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