Sui Jianfeng,Sun Hongfei,Gao Liugang,Xie Kai,Lin Tao,Ni Xinye.Relationship between the registration range and accuracy of CT images and CBCT images[J].Chinese Journal of Radiological Medicine and Protection,2017,37(4):306-310
Relationship between the registration range and accuracy of CT images and CBCT images
Received:October 21, 2016  
DOI:10.3760/cma.j.issn.0254-5098.2017.04.015
KeyWords:Cone beam computed tomography  Computed tomography  Range of registration  Accuracy  Segmentation
FundProject:江苏省自然科学基金(BK20151181)
Author NameAffiliationE-mail
Sui Jianfeng Department of Radiation Oncology, Second People's Hospital of Changzhou Affiliated to Nanjing Medical University, Changzhou 213003, China  
Sun Hongfei Department of Radiation Oncology, Second People's Hospital of Changzhou Affiliated to Nanjing Medical University, Changzhou 213003, China  
Gao Liugang Department of Radiation Oncology, Second People's Hospital of Changzhou Affiliated to Nanjing Medical University, Changzhou 213003, China  
Xie Kai Department of Radiation Oncology, Second People's Hospital of Changzhou Affiliated to Nanjing Medical University, Changzhou 213003, China  
Lin Tao Department of Radiation Oncology, Second People's Hospital of Changzhou Affiliated to Nanjing Medical University, Changzhou 213003, China  
Ni Xinye Department of Radiation Oncology, Second People's Hospital of Changzhou Affiliated to Nanjing Medical University, Changzhou 213003, China nxy2000@aliyun.com 
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Abstract::
      Objective To investigate the impact on registration accuracy with the different registration ranges of CBCT images and CT images. Methods CBCT and CT scans were performed on the of 5 patients. The registration ranges of five patients' images of abdomen, head and chest performed CBCT and CT scanning were processed with four modes. Mode 1: the registration range of CT images was larger than the registration range of CBCT images, mode 2: the registration range of CT images and CBCT images were equally, mode 3: taking a 5 cm translation of CT images range from mode 2, mode 4: The CBCT range and CT range reduced 2 cm both sides simultaneously from mode 2. Using the registration program from Insight Segmentation and Registration Toolkit(ITK)to the four modes, the Mean Square Difference(MSD) metric values of four modes after registration were compared and the relationship between mode 2 and another three modes was analyzed by paired t test. Results For the MSD metric values, mode 3 was maximum, mode 2 and 4 were minimum, and mode 1 was centered. The difference between the mode 2 and mode 4 was not statistically significant(P>0.05).The difference between the mode 2 and mode 1 was statistically significant(t=-4.586, -4.164, -5.618, P<0.05). The difference between the mode 2 and mode 3 was statistically significant(t=-6.423, -8.109, -19.601, P<0.05). Conclusion The registration ranges of CBCT and CT images has a certain extent of influence on the accuracy of image registration. The closer the registration range of CBCT and CT is, the higher the registration accuracy is.
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