| Peng Qian,Wang Pei,Wang Xianliang,Tan Yan,Wu Junxiang.Comparison of graphical optimization and inverse planning simulated annealing for brachytherapy of cervix cancers[J].Chinese Journal of Radiological Medicine and Protection,2016,36(12):909-912 |
| Comparison of graphical optimization and inverse planning simulated annealing for brachytherapy of cervix cancers |
| Received:June 28, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.12.006 |
| KeyWords:Cervix cancer Brachytherapy Graphical optimization Inverse simulated annealing optimization Dosimetry |
| FundProject:四川省科技支撑计划项目（2014SZ0001） |
| Author Name | Affiliation | E-mail | | Peng Qian | Department of Oncology, Sichuan Academy of Medical Science & Sichuan Provincial People's Hospital, Chengdu 610072, China | | | Wang Pei | Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu 610041, China | dengwangpei@163.com | | Wang Xianliang | Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu 610041, China | | | Tan Yan | Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu 610041, China | | | Wu Junxiang | Department of Radiation Oncology, Sichuan Cancer Hospital, Chengdu 610041, China | |
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| Abstract:: |
| Objective To compare the differences and characteristics of the dose distribution of the two optimization methods in the three dimensional brachytherapy, and provide the basis for clinical treatment. Methods Excel 2007 was used to generate random number. And a total of 21 patients of cervical cancer were selected from those who have completed the treatment. Inverse simulated annealing optimization (IPSA) plans were designed for graphical optimization (GO) plans. The dose volume histogram (DVH) parameters of the targets (V100%, V150%) and the organs (D1 cm3, D2 cm3) of the two methods were analyzed. Results The targets dose of both plans could meet the prescription requirements. There was no statistically significant difference in the dose parameters of all targets (P>0.05).The doses of D1 cm3 and D2 cm3 in the bladder of IPSA plan were significantly lower than that of the GO plan (t=3.596, 3.490, P<0.05).There was no statistically significant difference in the dose parameters of rectum (P>0.05). Conclusions For cervix brachytherapy, the GO and IPSA have no effect on targets dose, but IPSA optimization can reduce the maximum dose of bladder. |
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