| Li Kaixin,Chen Yuanyuan,Chen Ming,et al.Research progress on radiation induced oral mucositis[J].Chinese Journal of Radiological Medicine and Protection,2016,36(11):875-880 |
| Research progress on radiation induced oral mucositis |
| Received:May 25, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.11.015 |
| KeyWords:Radiation-induced oral mucositis Radiotherapy Side effect |
| FundProject:国家自然科学基金（81672971） |
| Author Name | Affiliation | E-mail | | Li Kaixin | Department of Radiation Oncology, First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou 362000, China | | | Chen Yuanyuan | Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou 310000, China | chenyy@zjcc.org.cn | | Chen Ming | Department of Radiation Oncology, Zhejiang Cancer Hospital, Hangzhou 310000, China | | | Xin Peiling | Department of Radiation Oncology, First Hospital of Quanzhou Affiliated to Fujian Medical University, Quanzhou 362000, China | |
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| Abstract:: |
| Radiation-induced oral mucositis (ROM) is a major complication in radiotherapy of head and neck. Mucositis is related to concurrent chemotherapy as well as altered fractionation schedules. The clinical symptoms associated with mucositis include oral pain, oral intake reduced, and secondary infections, which may lead to treatment interruption, suboptimal disease control, and poor quality of life. Hence, prevention and management of ROM is very important. In this review, some recent topics in terminology, prevalence, pathophysiology, clinical appearance, prophylaxis and treatment of mucositis related to radiation therapy are discussed. |
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