| Ji Zhe,Jiang Yuliang,Guo Fuxin,Sun Haitao,Fan Jinghong,Zhang Lujing,Wang Junjie.Dosimetry verification of radioactive seed implantation for malignant tumor assisted by 3D printing individual guide template[J].Chinese Journal of Radiological Medicine and Protection,2016,36(9):662-666 |
| Dosimetry verification of radioactive seed implantation for malignant tumor assisted by 3D printing individual guide template |
| Received:March 19, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.09.005 |
| KeyWords:3D printing Radioactive seed implantation Dosimetry Cancer |
| FundProject:首都临床特色应用研究与成果推广科研项目（Z151100004015171） |
| Author Name | Affiliation | E-mail | | Ji Zhe | Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China | | | Jiang Yuliang | Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China | | | Guo Fuxin | Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China | | | Sun Haitao | Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China | | | Fan Jinghong | Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China | | | Zhang Lujing | Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China | | | Wang Junjie | Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China | junjiewang_edu@sina.cn |
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| Abstract:: |
| Objective To compare the dose distribution of postoperative plans with preoperative plans for 3D printing guide template assist radioactive seeds implantations, and explore the accuracy of treatment at dosimetry level. Methods A total of fourteen patients registered from Dec 2015 to Mar 2016 who were applied with 3D printing guide template assisted radioactive seed implantations in the hospital were included in this study. The preoperative planning design and 3D printing template production were performed for all patients. The dose related parameters including D90%, minimum peripheral dose (MPD), V100%, V150%, V200%, conformal index (CI), external index (EI), and homogeneity index (HI) were compared between pre- and post-operation. The paired t-test was used to perform the statistical analysis. Results A total of fourteen 3D printing individual templates were produced which included 16 treatment areas. Compared with preoperative plans, the mean value of V100%, D90% and V150% decreased while the mean value of V200% and MPD increased in postoperative plans. However, there was no significant difference between the two groups except for V100% (t=2.451, P<0.05). The differences of CI, EI, HI between two groups were not statistically significant (P>0.05). Conclusions The validation of actual dose distribution in postoperation assistied by 3D printing template in seed implantation shows that most of parameters could meet the expectation of preoperative plans, which indicates the improvement in accuracy for this new type of treatment. |
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