| Zhang Meng,Zhou Juying.The progresses of mechanistic studies of the effect of NF-κB on radiation damage[J].Chinese Journal of Radiological Medicine and Protection,2016,36(7):553-557 |
| The progresses of mechanistic studies of the effect of NF-κB on radiation damage |
| Received:September 22, 2015 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.07.016 |
| KeyWords:NF-κB Radiation damage NF-κB inhibitor |
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| Abstract:: |
| The number of people needed to accept radiotherapy is increasing with the higher incidence of tumor, and the continuous development of radiation therapy technology has extended the long-term survival of patients. Avoiding the occurrence of radiation damage is particularly important. Since NF-κB plays an important role in gene transcription and regulation of radiation damage, this article introduced the structure, activation and function of NF-κB, reviewed the findings of NF-κB alterations in radiation injuries of brain and lung, and sketched the studies of NF-κB inhibitor. |
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