| Zhang Yuyu,Li Ge,Liu Bailong,Jiang Xin,Gong Shouliang,Dong Lihua.The immune effect of radiotherapy on tumor[J].Chinese Journal of Radiological Medicine and Protection,2016,36(6):470-474 |
| The immune effect of radiotherapy on tumor |
| Received:May 24, 2015 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.06.015 |
| KeyWords:Tumor Radiotherapy Immunotherapy Immune response |
| FundProject: |
| Author Name | Affiliation | E-mail | | Zhang Yuyu | Department of Radiation Oncology, First Bethune Hospital of Jilin University, Changchun 130021, China | | | Li Ge | Department of Endocrinology, Changchun Hospital of Traditional Chinese Medicine, Changchun 130041, China | | | Liu Bailong | Department of Radiation Oncology, First Bethune Hospital of Jilin University, Changchun 130021, China | | | Jiang Xin | Department of Radiation Oncology, First Bethune Hospital of Jilin University, Changchun 130021, China | | | Gong Shouliang | Key Laboratory of Radiobiology, Ministry of Health, School of Public Health, Jilin University, Changchun 130021, China | | | Dong Lihua | Department of Radiation Oncology, First Bethune Hospital of Jilin University, Changchun 130021, China | drlhdong@163.com |
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| Abstract:: |
| Recently, immunologists have payed the attention to the effects of ionizing radiation on tumor immunity, and attempted to induce and improve anti-tumor immune effects with it. More and more evidences showed that by adopting exact radiotherapy scheme and irradiation dose, particularly combined with immunotherapy, could induce or regulate systemic immune response and contributed to tumor control and inflammatory occurrence. This paper reviewed the effects and mechanisms of radiotherapy on tumor immune and the results in combination with immunotherapy here for guiding the effective combined application of radiotherapy and immunotherapy. |
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