| Li Aijing,Song Aiqin,Pan Yuning,Zheng Jianjun.Application of low-tube-voltage combined with adaptive iterative reconstruction in lower extremity computed tomography angiography[J].Chinese Journal of Radiological Medicine and Protection,2016,36(6):465-469 |
| Application of low-tube-voltage combined with adaptive iterative reconstruction in lower extremity computed tomography angiography |
| Received:November 12, 2015 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.06.014 |
| KeyWords:Lower extremity Iterative reconstruction Computed tomography angiography Radiation dose Image noise |
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| Abstract:: |
| Objective To investigate the feasibility of low-tube-voltage in combination with the three-dimensional adaptive iterative dose reduction (AIDR-3D) algorithm in performing lower extremity computed tomography angiography (CTA). Methods A total of 60 patients suspicious of lower extremity arterial occlusion were randomized into control group (120 kV,n=30) and experimental group (100 kV,n=30). The CTA was undertaken with a 320-row scanner (Toshiba Aquilion ONE), and the images was reconstructed with filtered back projection (FBP) algorithm in control group and FBP as well as the AIDR-3D algorithm in experimental group. The subjective image quality, vascular density (VD), noise, signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and dose length product (DLP) were compared between two groups. Results The DLP was significantly lower in experimental group than that in control group[(503.5±104.7) vs. (1099.4±151.7) mGy·cm, t=15.7, P<0.05]. The images in experimental group with 100 kV and FBP protocol had significantly increased VD and noise (t=-3.13,-3.61, P<0.05) than that in the control. The images in experimental group with AIDR-3D had significantly lower noise and higher SNR and CNR than that with FBP (t=13.59, 2.14,P<0.05), also significantly lower noise and significantly higher VD, SNR, and CNR than that in the control (t=-3.75, -4.19, -4.15,P<0.05). Conclusions Low-tube-voltage (100 kV) combined with AIDR-3D reconstruction could significantly improve the image quality and reduce radiation dose in lower extremity CTA with a 320-row CT scanner. Trial registration Chinese clinical trial registry, ChiCTR-DPD-16008054. |
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