| Zheng Xu,Liu Yulong,Wang Youyou,et al.Prevention and treatment of a case with acute radiation sickness combined with severe local radiation injury infection at “5.7” accident in Nanjing[J].Chinese Journal of Radiological Medicine and Protection,2016,36(5):359-363 |
| Prevention and treatment of a case with acute radiation sickness combined with severe local radiation injury infection at “5.7” accident in Nanjing |
| Received:February 05, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.05.010 |
| KeyWords:192Ir radiation accident Bone marrow form of acute radiation sickness Radiation skin injury Infection |
| FundProject:江苏省临床医学科技专项(BL2014040);江苏省卫生计生委2014-2015年度预防医学科研课题(Y2015024);江苏省研究生培养创新工程项目(SJLX15-0580) |
| Author Name | Affiliation | E-mail | | Zheng Xu | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Liu Yulong | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | yulongliu2002@126.com | | Wang Youyou | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Yu Daojiang | Department of Plastic Surgery, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Bian Huahui | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Chen Weibo | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Li Yuan | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Bao Mingyue | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Guo Kailin | Department of Nuclear Emergency Center, Second Affiliated Hospital of Soochow University, Suzhou 215004, China | |
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| Abstract:: |
| Objective To explore the measures and treatment plans to be taken for infection prevention and control of mild bone marrow form of acute radiation sickness combined with severe local acute radiation damage.Methods Medical treatment of a patient suffering such a radiation sickness caused by 192Ir external exposure was based to observe the occurrence, development and prognosis of infection and clinical manifestations, analyse the etiology of the wound surface and other related laboratory indicators, and evaluate their curative effect of antibiotics and other comprehensive measures. Results In early phase, the patient had no fever and survived the critical phase. During the medical treatment, the wound surface was accompanied complicated bacterial infections, especially there always being by drug-resistant bacteria such as Acinetobacter baumannii, especially during debridement and myocutaneous flap transplantation. The infections were controlled effectively by the series of comprehensive treatment.Conclusions In order to prevent and control the infection of patient suffering acute radiation sickness combined with large area of severe local radiation injury, both systemic and local treatment should be considered together with reasonable application of antibiotics and other comprehensive measures. |
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