Meng Xinhua,Mu Wanling,Tao Lina,et al.Photon-counting CT versus conventional energy-integrating detector CT: A comparative study in low-dose pediatric chest imaging[J].Chinese Journal of Radiological Medicine and Protection,2026,46(5):540-546
Photon-counting CT versus conventional energy-integrating detector CT: A comparative study in low-dose pediatric chest imaging
Received:May 14, 2025  
DOI:10.3760/cma.j.cn112271-20250514-00168
KeyWords:Children  X-ray computed tomography  Photon-counting detector  Radiation dose
FundProject:河南省科技厅医学科技攻关计划项目(252102310073);郑州市基础研究与应用基础研究项目(2024ZZJCYJ007)
Author NameAffiliationE-mail
Meng Xinhua Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China  
Mu Wanling Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China  
Tao Lina Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China  
Luo Chenglong Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China  
Su Danyang Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China  
Liu Jinlong Siemens Healthineers, Beijing 100102, China  
Gao Jianbo Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China  
Zhou Yue Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China zhouyue779@163.com 
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Abstract::
      Objective To evaluate the differences in radiation dose, objectiveimage quality, and subjective image quality between photon-counting detector CT (PCD-CT) and conventional energy-integrating detector CT (EID-CT) when children underwent non-enhanced chest CT. Methods A total of 52 children who underwent non-contrast chest CT scans using photon-counting detector CT (PCD-CT) at the First Affiliated Hospital of Zhengzhou University between April 2024 and May 2025 were retrospectively enrolled. Otherwise 52 children who underwent non-contrast chest CT scans using energy-integrating detector CT (EID-CT) at the same institution between October 2023 and May 2025 also were retrospectively selected. Two radiologists subjectively evaluated image quality using a 5-point Likert scale and measured the CT values and noise levels in the upper lobes of both lungs, the lower lobes of both lungs in the areas of no obvious pulmonary markings, as well as in the aorta and back muscles at the same layer. The optimized signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), and radiation dose were calculated. Comparisons of SNR and CNR between the two groups were performed using independent samples t-tests or non-parametric tests, while subjective scores were compared using the Mann-Whitney U test. Results In the objective evaluations, the SNR and CNR of the lung on EID-CT images were lower than that on PCD-CT images, which showed statistically significant differences (Z=7.04-7.66, 7.05-7.68, t=6.61-17.38, P<0.05); the effective radiation dose (E) of PCD-CT were lower than traditional EID-CT in 6-9 and 7-12 groups, and showed statistically significant differences (t=2.99, 0.16, P<0.05). In the subjective evaluations, compared to the EID-CT images overall image quality scores were higher for the PCD-CT images, and the differences were statistically significant (Z=3.56-4.06,P<0.001). Conclusions Compared to EID-CT images the PCD-CT images have higher spatial resolution, tissue contrast and lower image noise.
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