He Jie,Zeng Fubin,Zhang Huojun.Organ-at-risk sparing in external beam radiotherapy for prostate cancer[J].Chinese Journal of Radiological Medicine and Protection,2026,46(1):108-116
Organ-at-risk sparing in external beam radiotherapy for prostate cancer
Received:November 03, 2024  
DOI:10.3760/cma.j.cn112271-20241103-00304
KeyWords:Prostate cancer  Radiotherapy  Organ at risk (ORA)
FundProject:长海医院"固海"计划(GH145-33)
Author NameAffiliationE-mail
He Jie School of Health Science and Engineering, University of Shanghai for Science and Technology, Shanghai 200093, China
Department of Radiation Therapy, First Affiliated Hospital of Naval Medical University, Shanghai 200433, China 
chyyzhj@163.com 
Zeng Fubin Department of Radiation Therapy, First Affiliated Hospital of Naval Medical University, Shanghai 200433, China  
Zhang Huojun Department of Radiation Therapy, First Affiliated Hospital of Naval Medical University, Shanghai 200433, China  
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Abstract::
      The organ-at-risk (OAR) sparing plays a critical role in radiotherapy for prostate cancer. Given their immediate proximity to the prostate gland anatomically, the bladder and rectum are identified as significant dose-sparing objects in radiotherapy for prostate cancer. Increasing radiation doses might lead to elevated risks of adverse reactions, such as radiation cystitis and proctitis, which significantly affect the quality of life (QoL) of patients. This paper reviews the OAR sparing strategies in radiotherapy for prostate cancer, aiming to effectively reduce radiation doses to the bladder and rectum and minimize the incidence of adverse reactions. This will help improve the QoL of patients.
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