| Liang Li,Yuan Long,Yu Changlin,et al.Expert consensus on clinical treatment of acute radiation syndrome from external irradiation[J].Chinese Journal of Radiological Medicine and Protection,2025,45(9):827-839 |
| Expert consensus on clinical treatment of acute radiation syndrome from external irradiation |
| Received:December 09, 2024 |
| DOI：10.3760/cma.j.cn112271-20241209-00468 |
| KeyWords:External irradiation Acute radiation sickness Dose estimation Diagnosis Treatment |
| FundProject: |
| Author Name | Affiliation | E-mail | | Liang Li | Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital, Beijing 100191, China | | | Yuan Long | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | yuanlong@nirp.chinacdc.cn | | Yu Changlin | Fifth Medical Center, Chinese PLA General Hospital, Beijing 100039, China | 13701183031@163.com | | Liu Qingjie | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Liu Yulong | Second Affiliated Hospital of Soochow University, Suzhou 215004, China | | | Yang Wenfeng | Fifth Medical Center, Chinese PLA General Hospital, Beijing 100039, China | | | Wang Jin | Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210008, China | | | Huang Weixu | Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou 510620, China | | | Liu Ying | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Lei Cuiping | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Chen Huifang | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Fu Ximing | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Cao Baoshan | Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital, Beijing 100191, China | | | Wang Mopei | Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital, Beijing 100191, China | | | Zhang Zhaohui | Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital, Beijing 100191, China | | | Xiao Yu | Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital, Beijing 100191, China | | | Chen Yamei | Department of Medical Oncology and Radiation Sickness, Peking University Third Hospital, Beijing 100191, China | | | Sun Quanfu | National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | |
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| Abstract:: |
| China emerges as a major country in nuclear energy development and the application of nuclear and radiologic technology. The diagnosis and treatment of acute radiation syndrom (ARS) caused by external irradiation represent a core function in the country's medical rescue of nuclear and radiological emergencies. Clinically, ARS manifests hematopoietic, gastrointestinal, cutaneous, and central nervous system syndromes, with specific clinical manifestations, signs, severity, and prognosis strongly correlated with radiation dose. China has established a number of national and provincial centers for treating radiation-induced damage. Nevertheless, most medical staff have limited experience in ARS treatment. This consensus presents a summary of recent experience in treating ARS of China. In combination with recommendations from international organizations such as the World Health Organization (WHO), this consensus proposes key evidence of critical clinical issues of ARS, covering all links in the rescue of external irradiation-induced ARS. Initially, clinical diagnosis, syndromes, and severe degrees should be determined based on clinical symptoms and dose estimates. It is necessary to normalize clinical treatment measures for hematopoietic recovery, gastrointestinal injury treatment, infection control, symptomatic treatment, and multi-organ function preservation. To this end, this consensus offers cautions. This consensus provides principles of treatment with traditional Chinese medicine, psychological intervention, and follow-up. Additionally, it highlights multidisciplinary collaboration. It is recommended that this consensus be applied in relevant treatment centers. |
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