| Wei Xindi,Chen Wei,Wang Jin,et al.An analysis of deaths in medical X-ray diagnostic workers in Jiangsu province during 1950-2021[J].Chinese Journal of Radiological Medicine and Protection,2025,45(7):655-662 |
| An analysis of deaths in medical X-ray diagnostic workers in Jiangsu province during 1950-2021 |
| Received:August 18, 2024 |
| DOI：10.3760/cma.j.cn112271-20240818-00308 |
| KeyWords:Medical diagnostic X-ray workers Risk of death Circulatory system diseases Carcinoma |
| FundProject:中国医学科学院医学与健康科技创新工程(2021-I2M-1-042);江苏省医学重点学科(JSZJ20232201) |
| Author Name | Affiliation | E-mail | | Wei Xindi | School of Public Health, Nanjing Medical University, Nanjing 211166, China | | | Chen Wei | Department of Radiation Protection, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Wang Jin | School of Public Health, Nanjing Medical University, Nanjing 211166, China
Department of Radiation Protection, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | jinwang@jscdc.cn | | Zhang Zihao | School of Public Health, Nanjing Medical University, Nanjing 211166, China | | | Miao Yuji | Department of Radiation Protection, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Zhou Yuanyuan | Department of Radiation Protection, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Fan Xiangyong | Department of Radiation Protection, Jiangsu Provincial Center for Disease Control and Prevention, Nanjing 210009, China | | | Wang Jinhan | Department of Radiobiology, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | | | Gu Yeqing | Department of Radiobiology, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | |
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| Abstract:: |
| Objective To study the risk and pattern of deaths caused by various diseases in the population and in the case of long-term occupational X-ray exposure. Methods Using a combination of retrospective and prospective cohort research methods, an exposure group of medical X-ray diagnostic workers who worked in the radiology department of Jiangsu Provincial Hospital between 1950 and 1980 and a control group of medical workers from other departments who did not work with radiolog during the same period in the same hospital were selected to form a study cohort. The cumulative number of person years of observation in the cohort during 1950-2011 was calculated, and the Cox regression model was used to calculate the risk of deaths of medical X-ray diagnostic workers for various diseases through adjusting sex, attained age, birth age, and starting working age. Results A total of 6 953 follow-up visits was completed to the cohort, including 3 649 in the radiation group and 3 304 in the control group, with a total of 347 362 person years of observation. There were 2 099 deaths in the cohort as of December 31, 2021. Cox regression results showed that diseases with a significantly higher risk of death in the radiation group compared with the control group were: all-cancer (R=1.20, 95%CI: 1.04-1.39, Z=2.56, P<0.05, including lung cancer R=1.52, 95%CI: 1.17-1.98, Z=3.10, P<0.01, and pancreatic cancer R=1.96, 95%CI: 1.11-3.46, Z=2.31, P<0.05); diseases of the circulatory system (R=1.29, 95%CI: 1.06-1.57, Z=2.58, P<0.01); endocrine, nutritional and metabolic diseases (R=1.90, 95%CI: 1.06-3.42, Z=2.14, P<0.05). Stratified analyses showed that, of male workers, the radiation group had an increased risk of death caused by all-cancer and lung cancer (Z=3.50, 2.92, P<0.01); of the age group at starting ages 26 to 30, the radiation group had an increased risk of death distributed to circulatory diseases (Z=2.06, P<0.05); and in the age group at attained ages elder than 61 years, the radiation group had an increased risk of death distributed to all cancers, lung cancer, and circulatory diseases (Z=2.90-4.31, P<0.01). Conclusions As has been shown, threre is an increasing risk of death distributed to lung cancer, pancreatic cancer, and circulatory diseases in medical X-ray diagnostic workers in Jiangsu province. Further in-depth research in related areas may be conducted in the future. |
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